UniProt data
UniProt name: LIGO2_HUMAN (Q7L985)
Gene name: LINGO2; Synonyms=LERN3, LRRN6C; ORFNames=UNQ9234/PRO31993
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 546-566, 21 AA, Helical. {ECO:0000255}.
Sequence: 606 AA
10 20 30 40 50 60
MLHTAISCWQ PFLGLAVVLI FMGSTIGCPA RCECSAQNKS VSCHRRRLIA IPEGIPIETK
70 80 90 100 110 120
ILDLSKNRLK SVNPEEFISY PLLEEIDLSD NIIANVEPGA FNNLFNLRSL RLKGNRLKLV
130 140 150 160 170 180
PLGVFTGLSN LTKLDISENK IVILLDYMFQ DLHNLKSLEV GDNDLVYISH RAFSGLLSLE
190 200 210 220 230 240
QLTLEKCNLT AVPTEALSHL RSLISLHLKH LNINNMPVYA FKRLFHLKHL EIDYWPLLDM
250 260 270 280 290 300
MPANSLYGLN LTSLSVTNTN LSTVPFLAFK HLVYLTHLNL SYNPISTIEA GMFSDLIRLQ
310 320 330 340 350 360
ELHIVGAQLR TIEPHSFQGL RFLRVLNVSQ NLLETLEENV FSSPRALEVL SINNNPLACD
370 380 390 400 410 420
CRLLWILQRQ PTLQFGGQQP MCAGPDTIRE RSFKDFHSTA LSFYFTCKKP KIREKKLQHL
430 440 450 460 470 480
LVDEGQTVQL ECSADGDPQP VISWVTPRRR FITTKSNGRA TVLGDGTLEI RFAQDQDSGM
490 500 510 520 530 540
YVCIASNAAG NDTFTASLTV KGFASDRFLY ANRTPMYMTD SNDTISNGTN ANTFSLDLKT
550 560 570 580 590 600
ILVSTAMGCF TFLGVVLFCF LLLFVWSRGK GKHKNSIDLE YVPRKNNGAV VEGEVAGPRR
FNMKMI
CATM prediction
The sequence of LIGO2_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 550 560 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | VSTAMGCFTFLGVVLFCFLLLFVWSRG | 7.1 | -51.0° | 2.4 | 45.0 | -11.2 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session