UniProt data
UniProt name: ARMX2_HUMAN (Q7L311)
Gene name: ARMCX2; Synonyms=ALEX2, KIAA0512
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 7-25, 19 AA, Helical. {ECO:0000255}.
Sequence: 632 AA
10 20 30 40 50 60
MSRVRDAGCV AAGIVIGAGA WYCVYKYTRG RDQTKKRMAK PKNRAVAGTG ARARAGLRAG
70 80 90 100 110 120
FTIDLGSGFS PPTPVRAEAE DRAQDEASAL DTVGAEAVAP AASSAEAQSG AGSQAQEADG
130 140 150 160 170 180
AGVGPKAESV VGAAMASAIA PPPGVTEALG AAEAPAMAGA PKVAEAPREA ETSRAAVPPG
190 200 210 220 230 240
TVVPTEAAAP TEVTEGPGVA APTKVAEAPG VASPTEAAEA PVPATPTGAA APTGAAESPG
250 260 270 280 290 300
TSGSPRTAVV PGTSAAKKAT PGAHTGAIPK ATSATGAVPK GGGKGVTRSR NGGKGKGKKS
310 320 330 340 350 360
KVEVDELGMG FRPGDGAAAA AAASANGGQA FLAEVPDSEE GESGWTDTES DSDSEPETQR
370 380 390 400 410 420
RGRGRRPVAM QKRPFPYEID EILGVRDLRK VLALLQKSDD PFIQQVALLT LSNNANYSCN
430 440 450 460 470 480
QETIRKLGGL PIIANMINKT DPHIKEKALM AMNNLSENYE NQGRLQVYMN KVMDDIMASN
490 500 510 520 530 540
LNSAVQVVGL KFLTNMTITN DYQHLLVNSI ANFFRLLSQG GGKIKVEILK ILSNFAENPD
550 560 570 580 590 600
MLKKLLSTQV PASFSSLYNS YVESEILINA LTLFEIIYDN LRAEVFNYRE FNKGSLFYLC
610 620 630
TTSGVCVKKI RALANHHDLL VKVKVIKLVN KF
CATM prediction
The sequence of ARMX2_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 10 20 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | VRDAGCVAAGIVIGAGAWYCVYKYT | 6.5 | -48.0° | 0.7 | 54.1 | -34.6 |
| Model 2 | VRDAGCVAAGIVIGAGAWYCVYKYT | 6.7 | -50.9° | 2.4 | 45.2 | -27.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 10, VAL, HA | A, 9, CYS, O | 3.15Å |
| B, 13, GLY, HA1 | A, 10, VAL, O | 2.69Å |
| B, 14, ILE, HA | A, 13, GLY, O | 2.70Å |
| A, 10, VAL, HA | B, 9, CYS, O | 3.15Å |
| A, 13, GLY, HA1 | B, 10, VAL, O | 2.69Å |
| A, 14, ILE, HA | B, 13, GLY, O | 2.70Å |
