Protein phosphatase 1 regulatory subunit 3F

UniProt data

UniProt name: PPR3F_HUMAN (Q6ZSY5)

Gene name: PPP1R3F

Organism: Homo sapiens (Human).

Function: Glycogen-targeting subunit for protein phosphatase 1 (PP1). {ECO:0000269|PubMed:21668450}.

Subcellular location: Membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Transmembrane domains:

  1. 769-789, 21 AA, Helical. {ECO:0000255}.

Sequence: 799 AA

10 20 30 40 50 60 MARTAPVEPP LRHSAPPSPA AGEPRTSVEA AVAPRRVLFA DEALGLPLAQ LRRYRPWGGP 70 80 90 100 110 120 GAGKMAAAAG QDGGGGGGAD EDDDGEDGDE GEEEEEACPE PSPLCPVPAG GGFYLVPTFS 130 140 150 160 170 180 LPPAPGRLER LGRVMVELEA LLPPPGAVPG GAGVWVPGGR PPVLRGLVRV LNRSFEKAVH 190 200 210 220 230 240 VRASHDGWAS FCDHPARYVP RSPPWAGAGG TGAGDPILDP GLGLGPGQAS ASSPDDGGRT 250 260 270 280 290 300 DRFAFQLPFA EGAGDGARLD FVVRYETPEG TFWANNHGRN YTVLLRIAPA PTPTDAEGLP 310 320 330 340 350 360 QQQQLPQLEP QPECQGPVEA EARQLKSCMK PVRRRPAEEE LKTKNMDDNT FAMAEHPDVQ 370 380 390 400 410 420 ESVGPLVAPT PLRPWPQMTL QVSDVPMTGN PAEEGDVPRS SPPVAFTEVL QAPAIRIPPS 430 440 450 460 470 480 SPLCGLGGSP RDQASGPDAS EGATGPFLEP SQQQAEATWG VSSENGGGLE AVSGSEELLG 490 500 510 520 530 540 EDTIDQELEQ LYLSHLSRLR AAVAAGGAGG GGEGSTDGGM SPSHPLGILT DRDLILKWPG 550 560 570 580 590 600 PERALNSALA EEITLHYARL GRGVELIKDT EDPDDEGEGE EGLSVTPSSP EGDSPKESPP 610 620 630 640 650 660 EILSGARSVV ATMGDVWLPW AEGSGCDGPV VLGTEGQFIG DPEKGMGKDT SSLHMNRVIA 670 680 690 700 710 720 GVTESLGEAG TEAQIEVTSE WAGSLDPISG KEPASPVLLQ GQNPTLLSPL GAEVCLSSVA 730 740 750 760 770 780 RPHVSSQDEK DAGPSLEPPK KSPTLAVPAE CVCALPPQLR GPLTQTLGVL AGLVVVPVAL 790 NSGVSLLVLA LCLSLAWFS

CATM prediction

The sequence of PPR3F_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
      770       780       790
    |    +    |    +    |  		 (Å) (°) (Å) (°)  
Model 1 TLGVLAGLVVVAVALNSGVSLLVLALC 6.7 -53.0° 5.2 58.0 -8.1
Prolines* TLGVLAGLVVVPVALNSGVSLLVLALC          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 772, GLY, HA1 A, 769, VAL, O 3.49Å
A, 772, GLY, HA1 B, 769, VAL, O 3.49Å