UniProt data
UniProt name: R9BP_HUMAN (Q6ZS82)
Gene name: RGS9BP; Synonyms=R9AP
Organism: Homo sapiens (Human).
Function: Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity). {ECO:0000250}.
Subcellular location: Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Transmembrane domains:
- 211-231, 21 AA, Helical; Anchor for type IV membrane protein. {ECO:0000255}.
Sequence: 235 AA
CATM prediction
The sequence of R9BP_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 210 220 230 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | ARKALAAILFGAVLLAAVALAVCVAKL | 7.3 | -51.0° | 4.3 | 40.5 | -3.9 |
| Prolines* | PRKALAAILFGAVLLAAVALAVCVAKL |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 215, ILE, HA | A, 214, ALA, O | 3.25Å |
| B, 218, GLY, HA1 | A, 215, ILE, O | 3.49Å |
| A, 215, ILE, HA | B, 214, ALA, O | 3.25Å |
| A, 218, GLY, HA1 | B, 215, ILE, O | 3.49Å |

