UniProt data
UniProt name: CEA20_HUMAN (Q6UY09)
Gene name: CEACAM20; ORFNames=UNQ9366/PRO34155
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 451-471, 21 AA, Helical. {ECO:0000255}.
Sequence: 585 AA
10 20 30 40 50 60
MGPADSWGHH WMGILLSASL CTVWSPPAAA QLTLNANPLD ATQSEDVVLP VFGTPRTPQI
70 80 90 100 110 120
HGRSRELAKP SIAVSPGTAI EQKDMVTFYC TTKDVNITIH WVSNNLSIVF HERMQLSKDG
130 140 150 160 170 180
KILTILIVQR EDSGTYQCEA RDALLSQRSD PIFLDVKYGP DPVEIKLESG VASGEVVEVM
190 200 210 220 230 240
EGSSMTFLAE TKSHPPCAYT WFLLDSILSH TTRTFTIHAV SREHEGLYRC LVSNSATHLS
250 260 270 280 290 300
SLGTLKVRVL ETLTMPQVVP SSLNLVENAR SVDLTCQTVN QSVNVQWFLS GQPLLPSEHL
310 320 330 340 350 360
QLSADNRTLI IHGLQRNDTG PYACEVWNWG SRARSEPLEL TINYGPDQVH ITRESASEMI
370 380 390 400 410 420
STIEAELNSS LTLQCWAESK PGAEYRWTLE HSTGEHLGEQ LIIRALTWEH DGIYNCTASN
430 440 450 460 470 480
SLTGLARSTS VLVKVVGPQS SSLSSGAIAG IVIGILAVIA VASELGYFLC IRNARRPSRK
490 500 510 520 530 540
TTEDPSHETS QPIPKEEHPT EPSSESLSPE YCNISQLQGR IRVELMQPPD LPEETYETKL
550 560 570 580
PSASRRGNSF SPWKPPPKPL MPPLRLVSTV PKNMESIYEV LGMQQ
CATM prediction
The sequence of CEA20_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 450 460 470 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | IAGIVIGILAVIAVASELGYFLCIRNA | 6.8 | -45.8° | 2.7 | 47.2 | -16.0 |
| Model 2 | IAGIVIGILAVIAVASELGYFLCIRNA | 6.6 | -55.0° | 5.0 | 53.0 | -7.2 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 463, SER, HA | A, 462, ALA, O | 2.81Å |
| B, 466, GLY, HA1 | A, 463, SER, O | 2.75Å |
| B, 467, TYR, HA | A, 466, GLY, O | 3.39Å |
| B, 470, CYS, HA | A, 467, TYR, OH | 3.14Å |
| A, 463, SER, HA | B, 462, ALA, O | 2.81Å |
| A, 466, GLY, HA1 | B, 463, SER, O | 2.75Å |
| A, 467, TYR, HA | B, 466, GLY, O | 3.39Å |
| A, 470, CYS, HA | B, 467, TYR, OH | 3.14Å |
