Butyrophilin-like protein 3

UniProt data

UniProt name: BTNL3_HUMAN (Q6UXE8)

Gene name: BTNL3; Synonyms=BTNLR, COLF4100; ORFNames=UNQ744/PRO1472

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Transmembrane domains:

  1. 238-258, 21 AA, Helical. {ECO:0000255}.

Sequence: 466 AA

10 20 30 40 50 60 MAFVLILVLS FYELVSGQWQ VTGPGKFVQA LVGEDAVFSC SLFPETSAEA MEVRFFRNQF 70 80 90 100 110 120 HAVVHLYRDG EDWESKQMPQ YRGRTEFVKD SIAGGRVSLR LKNITPSDIG LYGCWFSSQI 130 140 150 160 170 180 YDEEATWELR VAALGSLPLI SIVGYVDGGI QLLCLSSGWF PQPTAKWKGP QGQDLSSDSR 190 200 210 220 230 240 ANADGYSLYD VEISIIVQEN AGSILCSIHL AEQSHEVESK VLIGETFFQP SPWRLASILL 250 260 270 280 290 300 GLLCGALCGV VMGMIIVFFK SKGKIQAELD WRRKHGQAEL RDARKHAVEV TLDPETAHPK 310 320 330 340 350 360 LCVSDLKTVT HRKAPQEVPH SEKRFTRKSV VASQGFQAGK HYWEVDVGQN VGWYVGVCRD 370 380 390 400 410 420 DVDRGKNNVT LSPNNGYWVL RLTTEHLYFT FNPHFISLPP STPPTRVGVF LDYEGGTISF 430 440 450 460 FNTNDQSLIY TLLTCQFEGL LRPYIQHAMY DEEKGTPIFI CPVSWG

CATM prediction

The sequence of BTNL3_HUMAN returned 13 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
       240       250       26
+    |    +    |    +    | 		 (Å) (°) (Å) (°)  
Model 1 LASILLGLLCGALCGVVMGMIIVFFKS 6.4 -31.2° 6.0 55.0 -56.9
Model 2 LASILLGLLCGALCGVVMGMIIVFFKS 6.4 -37.9° 4.5 57.0 -43.2
Model 3 LASILLGLLCGALCGVVMGMIIVFFKS 6.2 -49.3° 2.2 59.1 -39.3
Model 4 LASILLGLLCGALCGVVMGMIIVFFKS 6.7 -48.0° -0.0 38.2 -38.1
Model 5 LASILLGLLCGALCGVVMGMIIVFFKS 7.3 -39.7° 2.0 44.0 -35.8
Model 6 LASILLGLLCGALCGVVMGMIIVFFKS 6.3 -55.0° 0.9 50.1 -34.4
Model 7 LASILLGLLCGALCGVVMGMIIVFFKS 6.5 -52.9° 5.3 57.9 -33.7
Model 8 LASILLGLLCGALCGVVMGMIIVFFKS 6.4 -54.9° 2.4 48.0 -32.9
Model 9 LASILLGLLCGALCGVVMGMIIVFFKS 7.3 -54.0° 3.6 49.0 -18.1
Model 10 LASILLGLLCGALCGVVMGMIIVFFKS 7.0 -53.0° 4.2 53.4 -16.2
Model 11 LASILLGLLCGALCGVVMGMIIVFFKS 7.1 -41.9° 2.0 32.9 -13.7
Model 12 LASILLGLLCGALCGVVMGMIIVFFKS 7.2 -27.9° 4.1 39.9 -9.3
Model 13 LASILLGLLCGALCGVVMGMIIVFFKS 7.1 -39.0° 3.9 54.0 -2.6

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 242, LEU, HA A, 241, GLY, O 2.63Å
B, 245, GLY, HA1 A, 242, LEU, O 2.63Å
B, 246, ALA, HA A, 245, GLY, O 2.41Å
B, 249, GLY, HA1 A, 246, ALA, O 3.32Å
A, 242, LEU, HA B, 241, GLY, O 2.63Å
A, 245, GLY, HA1 B, 242, LEU, O 2.63Å
A, 246, ALA, HA B, 245, GLY, O 2.41Å
A, 249, GLY, HA1 B, 246, ALA, O 3.32Å