UniProt data
UniProt name: PXDC2_HUMAN (Q6UX71)
Gene name: PLXDC2; Synonyms=TEM7R; ORFNames=UNQ2514/PRO6003
Organism: Homo sapiens (Human).
Function: May play a role in tumor angiogenesis. {ECO:0000269|PubMed:11559528}.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 455-475, 21 AA, Helical. {ECO:0000255}.
Sequence: 529 AA
10 20 30 40 50 60
MARFPKADLA AAGVMLLCHF FTDQFQFADG KPGDQILDWQ YGVTQAFPHT EEEVEVDSHA
70 80 90 100 110 120
YSHRWKRNLD FLKAVDTNRA SVGQDSPEPR SFTDLLLDDG QDNNTQIEED TDHNYYISRI
130 140 150 160 170 180
YGPSDSASRD LWVNIDQMEK DKVKIHGILS NTHRQAARVN LSFDFPFYGH FLREITVATG
190 200 210 220 230 240
GFIYTGEVVH RMLTATQYIA PLMANFDPSV SRNSTVRYFD NGTALVVQWD HVHLQDNYNL
250 260 270 280 290 300
GSFTFQATLL MDGRIIFGYK EIPVLVTQIS STNHPVKVGL SDAFVVVHRI QQIPNVRRRT
310 320 330 340 350 360
IYEYHRVELQ MSKITNISAV EMTPLPTCLQ FNRCGPCVSS QIGFNCSWCS KLQRCSSGFD
370 380 390 400 410 420
RHRQDWVDSG CPEESKEKMC ENTEPVETSS RTTTTVGATT TQFRVLTTTR RAVTSQFPTS
430 440 450 460 470 480
LPTEDDTKIA LHLKDNGAST DDSAAEKKGG TLHAGLIIGI LILVLIVATA ILVTVYMYHH
490 500 510 520
PTSAASIFFI ERRPSRWPAM KFRRGSGHPA YAEVEPVGEK EGFIVSEQC
CATM prediction
The sequence of PXDC2_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 460 470 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LHAGLIIGILILVLIVATAILVTVYMY | 7.1 | -55.0° | 5.8 | 47.0 | -6.6 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 456, LEU, HA | A, 455, GLY, O | 3.10Å |
| A, 456, LEU, HA | B, 455, GLY, O | 3.10Å |