UniProt data
UniProt name: F171B_HUMAN (Q6P995)
Gene name: FAM171B; Synonyms=KIAA1946; ORFNames=NPD019
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 354-374, 21 AA, Helical. {ECO:0000255}.
Sequence: 826 AA
10 20 30 40 50 60
MARLCRRVPC TLLLGLAVVL LKARLVPAAA RAELSRSDLS LIQQQQQQQQ QQQQQQKQLE
70 80 90 100 110 120
EAEEERTEVP GATSTLTVPV SVFMLKVQVN DIISRQYLSQ AVVEVFVNYT KTNSTVTKSN
130 140 150 160 170 180
GAVLIKVPYK LGLSLTIIAY KDGYVLTPLP WKTRRMPIYS SVTLSLFPQS QANIWLFEDT
190 200 210 220 230 240
VLITGKLADA KSQPSVQFSK ALIKLPDNHH ISNVTGYLTV LQQFLKVDNF LHTTGITLNK
250 260 270 280 290 300
PGFENIELTP LAAICVKIYS GGKELKVNGS IQVSLPLLRL NDISAGDRIP AWTFDMNTGA
310 320 330 340 350 360
WVNHGRGMVK EHNNHLIWTY DAPHLGYWIA APLPGTRGSG INEDSKDITA YHTVFLTAIL
370 380 390 400 410 420
GGTIVIVIGF FAVLLCYCRD KCGTPQKRER NITKLEVLKR DQTTSTTHIN HISTVKVALK
430 440 450 460 470 480
AEDKSQLFNA KNSSYSPQKK EPSKAETEER VSMVKTRDDF KIYNEDVSFL SVNQNNYSRN
490 500 510 520 530 540
PTQSLEPNVG SKQPKHINNN LSSSLGDAQD EKRYLTGNEE AYGRSHIPEQ LMHIYSQPIA
550 560 570 580 590 600
ILQTSDLFST PEQLHTAKSA TLPRKGQLVY GQLMEPVNRE NFTQTLPKMP IHSHAQPPDA
610 620 630 640 650 660
REEDIILEGQ QSLPSQASDW SRYSSSLLES VSVPGTLNEA VVMTPFSSEL QGISEQTLLE
670 680 690 700 710 720
LSKGKPSPHP RAWFVSLDGK PVAQVRHSFI DLKKGKRTQS NDTSLDSGVD MNELHSSRKL
730 740 750 760 770 780
EREKTFIKSM HQPKILYLED LDLSSSESGT TVCSPEDPAL RHILDGGSGV IMEHPGEESP
790 800 810 820
GRKSTVEDFE ANTSPTKRRG RPPLAKRDSK TNIWKKREER PLIPIN
CATM prediction
The sequence of F171B_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 360 370 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | YHTVFLTAILGGTIVIVIGFFAVLLCY | 7.1 | -54.1° | 2.6 | 32.9 | -21.7 |
| Model 2 | YHTVFLTAILGGTIVIVIGFFAVLLCY | 7.2 | -54.0° | 3.6 | 49.2 | -16.7 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 358, ALA, HA | A, 357, THR, O | 3.38Å |
| B, 361, GLY, HA1 | A, 358, ALA, O | 3.04Å |
| A, 358, ALA, HA | B, 357, THR, O | 3.38Å |
| A, 361, GLY, HA1 | B, 358, ALA, O | 3.04Å |
