Fc receptor-like protein 6

UniProt data

UniProt name: FCRL6_HUMAN (Q6DN72)

Gene name: FCRL6; Synonyms=FCRH6

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 308-328, 21 AA, Helical. {ECO:0000255}.

Sequence: 434 AA

10 20 30 40 50 60 MLLWTAVLLF VPCVGKTVWL YLQAWPNPVF EGDALTLRCQ GWKNTPLSQV KFYRDGKFLH 70 80 90 100 110 120 FSKENQTLSM GAATVQSRGQ YSCSGQVMYI PQTFTQTSET AMVQVQELFP PPVLSAIPSP 130 140 150 160 170 180 EPREGSLVTL RCQTKLHPLR SALRLLFSFH KDGHTLQDRG PHPELCIPGA KEGDSGLYWC 190 200 210 220 230 240 EVAPEGGQVQ KQSPQLEVRV QAPVSRPVLT LHHGPADPAV GDMVQLLCEA QRGSPPILYS 250 260 270 280 290 300 FYLDEKIVGN HSAPCGGTTS LLFPVKSEQD AGNYSCEAEN SVSRERSEPK KLSLKGSQVL 310 320 330 340 350 360 FTPASNWLVP WLPASLLGLM VIAAALLVYV RSWRKAGPLP SQIPPTAPGG EQCPLYANVH 370 380 390 400 410 420 HQKGKDEGVV YSVVHRTSKR SEARSAEFTV GRKDSSIICA EVRCLQPSEV SSTEVNMRSR 430 TLQEPLSDCE EVLC

CATM prediction

The sequence of FCRL6_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
       310       320       33
+    |    +    |    +    | 		 (Å) (°) (Å) (°)  
Model 1 SNWLVAWLAASLLGLMVIAAALLVYVR 7.3 -34.0° 2.7 38.0 -7.2
Prolines* SNWLVPWLPASLLGLMVIAAALLVYVR          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 311, TRP, HA A, 310, ALA, O 3.45Å
A, 311, TRP, HA B, 310, ALA, O 3.45Å