UniProt data
UniProt name: LEMD1_HUMAN (Q68G75)
Gene name: LEMD1
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 152-172, 21 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 181 AA
10 20 30 40 50 60
MVDVKCLSDC KLQNQLEKLG FSPGPILPST RKLYEKKLVQ LLVSPPCAPP VMNGPRELDG
70 80 90 100 110 120
AQDSDDSEEL NIILQGNIIL STEKSKKLKK WPEASTTKRK AVDTYCLDYK PSKGRRWAAR
130 140 150 160 170 180
APSTRITYGT ITKERDYCAE DQTIESWREE GFPVGLKLAV LGIFIIVVFV YLTVENKSLF
G
CATM prediction
The sequence of LEMD1_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 150 160 170 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | EEGFAVGLKLAVLGIFIIVVFVYLTVE | 6.7 | -39.0° | 6.0 | 45.0 | -11.2 |
| Prolines* | EEGFPVGLKLAVLGIFIIVVFVYLTVE |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 155, GLY, HA1 | A, 152, PHE, O | 3.27Å |
| A, 155, GLY, HA1 | B, 152, PHE, O | 3.27Å |