UniProt data
UniProt name: LYSM4_HUMAN (Q5XG99)
Gene name: LYSMD4
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 218-238, 21 AA, Helical. {ECO:0000255}.
Sequence: 296 AA
10 20 30 40 50 60
MRHEELLTKT FQGPAVVCGT PTSHVYMFKN GSGDSGDSSE EESHRVVLRP RGKERHKSGV
70 80 90 100 110 120
HQPPQAGAGD VVLLQRELAQ EDSLNKLALQ YGCKVADIKK VNNFIREQDL YALKSVKIPV
130 140 150 160 170 180
RNHGILMETH KELKPLLSPS SETTVTVELP EADRAGAGTG AQAGQLMGFF KGIDQDIERA
190 200 210 220 230 240
VQSEIFLHES YCMDTSHQPL LPAPPKTPMD GADCGIQWWN AVFIMLLIGI VLPVFYLVYF
250 260 270 280 290
KIQASGETPN SLNTTVIPNG SMAMGTVPGQ APRLAVAVPA VTSADSQFSQ TTQAGS
CATM prediction
The sequence of LYSM4_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 220 230 24 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | GIQWWNAVFIMLLIGIVLAVFYLVYFK | 7.0 | -54.8° | 2.4 | 48.3 | -30.6 |
| Prolines* | GIQWWNAVFIMLLIGIVLPVFYLVYFK |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 226, LEU, HA | A, 225, MET, O | 3.33Å |
| B, 229, GLY, HA1 | A, 226, LEU, O | 2.98Å |
| A, 226, LEU, HA | B, 225, MET, O | 3.33Å |
| A, 229, GLY, HA1 | B, 226, LEU, O | 2.98Å |