UniProt data
UniProt name: FA69B_HUMAN (Q5VUD6)
Gene name: FAM69B; Synonyms=C9orf136; ORFNames=PP6977
Organism: Homo sapiens (Human).
Function:
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Transmembrane domains:
- 31-51, 21 AA, Helical. {ECO:0000255}.
Sequence: 431 AA
10 20 30 40 50 60
MRRLRRLAHL VLFCPFSKRL QGRLPGLRVR CIFLAWLGVF AGSWLVYVHY SSYSERCRGH
70 80 90 100 110 120
VCQVVICDQY RKGIISGSVC QDLCELHMVE WRTCLSVAPG QQVYSGLWRD KDVTIKCGIE
130 140 150 160 170 180
ETLDSKARSD AAPRRELVLF DKPTRGTSIK EFREMTLSFL KANLGDLPSL PALVGQVLLM
190 200 210 220 230 240
ADFNKDNRVS LAEAKSVWAL LQRNEFLLLL SLQEKEHASR LLGYCGDLYL TEGVPHGAWH
250 260 270 280 290 300
AAALPPLLRP LLPPALQGAL QQWLGPAWPW RAKIAIGLLE FVEELFHGSY GTFYMCETTL
310 320 330 340 350 360
ANVGYTATYD FKMADLQQVA PEATVRRFLQ GRRCEHSTDC TYGRDCRAPC DRLMRQCKGD
370 380 390 400 410 420
LIQPNLAKVC ALLRGYLLPG APADLREELG TQLRTCTTLS GLASQVEAHH SLVLSHLKTL
430
LWKKISNTKY S
CATM prediction
The sequence of FA69B_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 30 40 50 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | RVRCIFLAWLGVFAGSWLVYVHYSSYS | 6.8 | -48.3° | 0.7 | 54.1 | -11.6 |
| Model 2 | RVRCIFLAWLGVFAGSWLVYVHYSSYS | 7.4 | -50.0° | 2.8 | 47.0 | -7.2 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 35, ALA, HA | A, 34, LEU, O | 3.40Å |
| B, 38, GLY, HA1 | A, 35, ALA, O | 2.95Å |
| B, 39, VAL, HA | A, 38, GLY, O | 2.98Å |
| A, 35, ALA, HA | B, 34, LEU, O | 3.40Å |
| A, 38, GLY, HA1 | B, 35, ALA, O | 2.95Å |
| A, 39, VAL, HA | B, 38, GLY, O | 2.98Å |
