Protein FAM209A

UniProt data

UniProt name: F209A_HUMAN (Q5JX71)

Gene name: FAM209A; Synonyms=C20orf106

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 53-73, 21 AA, Helical. {ECO:0000255}.

Sequence: 171 AA

10 20 30 40 50 60 MWTLKSSLVL LLCLTCSYAF MFSSLRQKTS EPQGKVQYGE HFRIRQNLPE HTQGWLGSKW 70 80 90 100 110 120 LWLLFVVVPF VILQCQRDSE KNKEQSPPGL RGGQLHSPLK KKRNASPNKD CAFNTLMELE 130 140 150 160 170 VELMKFVSKV RNLKRAMATG SGSNLRLRKS EMPADPYHVT ICEIWGEESS S

CATM prediction

The sequence of F209A_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
  50        60        70     
|    +    |    +    |    + 		 (Å) (°) (Å) (°)  
Model 1 EHTQGWLGSKWLWLLFVVVAFVILQCQ 6.6 -46.0° 2.7 47.0 -14.8
Model 2 EHTQGWLGSKWLWLLFVVVAFVILQCQ 7.2 -48.0° 3.3 33.9 -1.6
Prolines* EHTQGWLGSKWLWLLFVVVPFVILQCQ          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 55, TRP, HA A, 54, GLY, O 3.21Å
B, 58, SER, HG1 A, 55, TRP, O 2.64Å
A, 55, TRP, HA B, 54, GLY, O 3.20Å
A, 58, SER, HG1 B, 55, TRP, O 2.64Å