UniProt data
UniProt name: NADL2_HUMAN (Q58DX5)
Gene name: NAALADL2
Organism: Homo sapiens (Human).
Function: May be catalytically inactive.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Transmembrane domains:
- 122-142, 21 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 795 AA
10 20 30 40 50 60
MGENEASLPN TSLQGKKMAY QKVHADQRAP GHSQYLDNDD LQATALDLEW DMEKELEESG
70 80 90 100 110 120
FDQFQLDGAE NQNLGHSETI DLNLDSIQPA TSPKGRFQRL QEESDYITHY TRSAPKSNRC
130 140 150 160 170 180
NFCHVLKILC TATILFIFGI LIGYYVHTNC PSDAPSSGTV DPQLYQEILK TIQAEDIKKS
190 200 210 220 230 240
FRNLVQLYKN EDDMEISKKI KTQWTSLGLE DVQFVNYSVL LDLPGPSPST VTLSSSGQCF
250 260 270 280 290 300
HPNGQPCSEE ARKDSSQDLL YSYAAYSAKG TLKAEVIDVS YGMADDLKRI RKIKNVTNQI
310 320 330 340 350 360
ALLKLGKLPL LYKLSSLEKA GFGGVLLYID PCDLPKTVNP SHDTFMVSLN PGGDPSTPGY
370 380 390 400 410 420
PSVDESFRQS RSNLTSLLVQ PISAPLVAKL ISSPKARTKN EACSSLELPN NEIRVVSMQV
430 440 450 460 470 480
QTVTKLKTVT NVVGFVMGLT SPDRYIIVGS HHHTAHSYNG QEWASSTAII TAFIRALMSK
490 500 510 520 530 540
VKRGWRPDRT IVFCSWGGTA FGNIGSYEWG EDFKKVLQKN VVAYISLHSP IRGNSSLYPV
550 560 570 580 590 600
ASPSLQQLVV EKNNFNCTRR AQCPETNISS IQIQGDADYF INHLGVPIVQ FAYEDIKTLE
610 620 630 640 650 660
GPSFLSEARF STRATKIEEM DPSFNLHETI TKLSGEVILQ IANEPVLPFN ALDIALEVQN
670 680 690 700 710 720
NLKGDQPNTH QLLAMALRLR ESAELFQSDE MRPANDPKER APIRIRMLND ILQDMEKSFL
730 740 750 760 770 780
VKQAPPGFYR NILYHLDEKT SRFSILIEAW EHCKPLASNE TLQEALSEVL NSINSAQVYF
790
KAGLDVFKSV LDGKN
CATM prediction
The sequence of NADL2_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 120 130 140 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | RCNFCHVLKILCTATILFIFGILIGYY | 6.8 | -47.7° | 0.7 | 54.1 | -21.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 136, PHE, HA | A, 135, LEU, O | 3.46Å |
| B, 139, GLY, HA1 | A, 136, PHE, O | 3.03Å |
| B, 140, ILE, HA | A, 139, GLY, O | 2.99Å |
| A, 136, PHE, HA | B, 135, LEU, O | 3.46Å |
| A, 139, GLY, HA1 | B, 136, PHE, O | 3.03Å |
| A, 140, ILE, HA | B, 139, GLY, O | 2.99Å |