UniProt data
UniProt name: VAS1L_HUMAN (Q52LC2)
Gene name: ATP6AP1L
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 147-167, 21 AA, Helical. {ECO:0000255}.
Sequence: 224 AA
10 20 30 40 50 60
MRLWKARVLK LVLKTAKDSR LGLNSKWLSL KLGDAGNPRS LAIRFILTNY NKLSIQSWFS
70 80 90 100 110 120
LRRVEIISNN SIQAVFNPTG VYAPSGYSYR CQRVGSLQQD QALLLPSDTD DGSSLWEVTF
130 140 150 160 170 180
IDFQIQGFAI KGGRFTKAQD CASSFSPAFL IGLAMSLILL LVLAYALHML IYLRYLDQQY
190 200 210 220
DLIASPAHFS QLKARDTAEE KELLRSQGAE CYKLRSQQIS KIYV
CATM prediction
The sequence of VAS1L_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 150 160 1 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | SFSAAFLIGLAMSLILLLVLAYALHML | 7.3 | -43.0° | 3.5 | 49.9 | -20.8 |
| Model 2 | SFSAAFLIGLAMSLILLLVLAYALHML | 7.4 | -22.0° | 3.1 | 40.0 | -4.0 |
| Prolines* | SFSPAFLIGLAMSLILLLVLAYALHML |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 149, PHE, HA | A, 148, ALA, O | 3.19Å |
| B, 152, GLY, HA1 | A, 149, PHE, O | 3.43Å |
| B, 153, LEU, HA | A, 156, SER, OG | 2.73Å |
| A, 149, PHE, HA | B, 148, ALA, O | 3.19Å |
| A, 152, GLY, HA1 | B, 149, PHE, O | 3.43Å |
| A, 153, LEU, HA | B, 156, SER, OG | 2.73Å |
