UniProt data
UniProt name: CEA21_HUMAN (Q3KPI0)
Gene name: CEACAM21; ORFNames=UNQ3098/PRO10075
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 241-261, 21 AA, Helical. {ECO:0000255}.
Sequence: 293 AA
10 20 30 40 50 60
MGPPSACPHR ECIPWQGLLL TASLLTFWNA PTTAWLFIAS APFEVAEGEN VHLSVVYLPE
70 80 90 100 110 120
NLYSYGWYKG KTVEPNQLIA AYVIDTHVRT PGPAYSGRET ISPSGDLHFQ NVTLEDTGYY
130 140 150 160 170 180
TLQVTYRNSQ IEQASHHLRV YESVAQPSIQ ASSTTVTEKG SVVLTCHTNN TGTSFQWIFN
190 200 210 220 230 240
NQRLQVTKRM KLSWFNHMLT IDPIRQEDAG EYQCEVSNPV SSNRSDPLKL TVKSDDNTLG
250 260 270 280 290
ILIGVLVGSL LVAALVCFLL LRKTGRASDQ SDFREQQPPA STPGHGPSDS SIS
CATM prediction
The sequence of CEA21_HUMAN returned 5 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 240 250 260 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | TLGILIGVLVGSLLVAALVCFLLLRKT | 6.3 | -44.8° | 2.7 | 60.8 | -33.2 |
| Model 2 | TLGILIGVLVGSLLVAALVCFLLLRKT | 6.8 | -25.0° | 5.5 | 50.0 | -23.9 |
| Model 3 | TLGILIGVLVGSLLVAALVCFLLLRKT | 6.6 | -48.0° | 0.8 | 53.8 | -22.7 |
| Model 4 | TLGILIGVLVGSLLVAALVCFLLLRKT | 6.4 | -38.0° | 6.0 | 59.0 | -15.5 |
| Model 5 | TLGILIGVLVGSLLVAALVCFLLLRKT | 6.5 | -55.0° | 3.6 | 63.0 | -8.0 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 244, GLY, HA1 | A, 241, ILE, O | 2.70Å |
| B, 245, VAL, HA | A, 244, GLY, O | 3.31Å |
| A, 244, GLY, HA1 | B, 241, ILE, O | 2.70Å |
| A, 245, VAL, HA | B, 244, GLY, O | 3.31Å |
