HLA class I histocompatibility antigen, B-73 alpha chain

UniProt data

UniProt name: 1B73_HUMAN (Q31612)

Gene name: HLA-B; Synonyms=HLAB

Organism: Homo sapiens (Human).

Function: Involved in the presentation of foreign antigens to the immune system.

Subcellular location: Membrane; Single-pass type I membrane protein.

Transmembrane domains:

  1. 309-333, 25 AA, Helical. {ECO:0000255}.

Sequence: 363 AA

10 20 30 40 50 60 MLVMAPRTVL LLLSAALALT ETWAGSHSMR YFHTSVSRPG RGEPRFITVG YVDDTQFVRF 70 80 90 100 110 120 DSDAASPREE PRAPWIEQEG PEYWDRNTQI CKAKAQTDRV GLRNLRGYYN QSEDGSHTWQ 130 140 150 160 170 180 TMYGCDMGPD GRLLRGYNQF AYDGKDYIAL NEDLRSWTAA DTAAQITQRK WEAARVAEQL 190 200 210 220 230 240 RAYLEGECVE WLRRHLENGK ETLQRADPPK THVTHHPISD HEATLRCWAL GFYPAEITLT 250 260 270 280 290 300 WQRDGEDQTQ DTELVETRPA GDGTFQKWAA VVVPSGQEQR YTCHVQHEGL QEPCTLRWKP 310 320 330 340 350 360 SSQSTIPIVG IVAGLAVLVV TVAVVAVVAA VMCRRKSSGG KGGSYSQAAS SDSAQGSDVS LTA

CATM prediction

The sequence of 1B73_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
      310       320       330    
    |    +    |    +    |    + 		 (Å) (°) (Å) (°)  
Model 1 IAIVGIVAGLAVLVVTVAVVAVVAAVMCRRK 7.3 -51.0° 2.4 45.0 -0.6
Prolines* IPIVGIVAGLAVLVVTVAVVAVVAAVMCRRK          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session