UniProt data
UniProt name: MPEG1_HUMAN (Q2M385)
Gene name: MPEG1
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 656-676, 21 AA, Helical. {ECO:0000255}.
Sequence: 716 AA
10 20 30 40 50 60
MNNFRATILF WAAAAWAKSG KPSGEMDEVG VQKCKNALKL PVLEVLPGGG WDNLRNVDMG
70 80 90 100 110 120
RVMELTYSNC RTTEDGQYII PDEIFTIPQK QSNLEMNSEI LESWANYQSS TSYSINTELS
130 140 150 160 170 180
LFSKVNGKFS TEFQRMKTLQ VKDQAITTRV QVRNLVYTVK INPTLELSSG FRKELLDISD
190 200 210 220 230 240
RLENNQTRMA TYLAELLVLN YGTHVTTSVD AGAALIQEDH LRASFLQDSQ SSRSAVTASA
250 260 270 280 290 300
GLAFQNTVNF KFEENYTSQN VLTKSYLSNR TNSRVQSIGG VPFYPGITLQ AWQQGITNHL
310 320 330 340 350 360
VAIDRSGLPL HFFINPNMLP DLPGPLVKKV SKTVETAVKR YYTFNTYPGC TDLNSPNFNF
370 380 390 400 410 420
QANTDDGSCE GKMTNFSFGG VYQECTQLSG NRDVLLCQKL EQKNPLTGDF SCPSGYSPVH
430 440 450 460 470 480
LLSQIHEEGY NHLECHRKCT LLVFCKTVCE DVFQVAKAEF RAFWCVASSQ VPENSGLLFG
490 500 510 520 530 540
GLFSSKSINP MTNAQSCPAG YFPLRLFENL KVCVSQDYEL GSRFAVPFGG FFSCTVGNPL
550 560 570 580 590 600
VDPAISRDLG APSLKKCPGG FSQHPALISD GCQVSYCVKS GLFTGGSLPP ARLPPFTRPP
610 620 630 640 650 660
LMSQAATNTV IVTNSENARS WIKDSQTHQW RLGEPIELRR AMNVIHGDGG GLSGGAAAGV
670 680 690 700 710
TVGVTTILAV VITLAIYGTR KFKKKAYQAI EERQSLVPGT AATGDTTYQE QGQSPA
CATM prediction
The sequence of MPEG1_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 660 670 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | SGGAAAGVTVGVTTILAVVITLAIYGT | 6.7 | -28.0° | 6.0 | 47.0 | -19.5 |
| Model 2 | SGGAAAGVTVGVTTILAVVITLAIYGT | 6.3 | -49.0° | 2.3 | 59.0 | -14.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 659, GLY, HA1 | A, 656, ALA, O | 3.32Å |
| A, 659, GLY, HA1 | B, 656, ALA, O | 3.32Å |
