FXYD domain-containing ion transport regulator 3

UniProt data

UniProt name: FXYD3_HUMAN (Q14802)

Gene name: FXYD3; Synonyms=MAT8, PLML

Organism: Homo sapiens (Human).

Function: Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes. May be a modulator capable of activating endogenous oocyte channels.

Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 39-59, 21 AA, Helical. {ECO:0000255}.

Sequence: 87 AA

10 20 30 40 50 60 MQKVTLGLLV FLAGFPVLDA NDLEDKNSPF YYDWHSLQVG GLICAGVLCA MGIIIVMSAK 70 80 CKCKFGQKSG HHPGETPPLI TPGSAQS

CATM prediction

The sequence of FXYD3_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
      40        50        60 
    |    +    |    +    |  		 (Å) (°) (Å) (°)  
Model 1 SLQVGGLICAGVLCAMGIIIVMSAKCK 7.3 -35.0° 5.0 35.0 -3.9
Model 2 SLQVGGLICAGVLCAMGIIIVMSAKCK 7.4 -47.9° 0.5 46.7 -3.9

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session