UniProt data
UniProt name: KLRD1_HUMAN (Q13241)
Gene name: KLRD1; Synonyms=CD94
Organism: Homo sapiens (Human).
Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Subcellular location: Membrane; Single-pass type II membrane protein.
Transmembrane domains:
- 11-31, 21 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 179 AA
10 20 30 40 50 60
MAVFKTTLWR LISGTLGIIC LSLMSTLGIL LKNSFTKLSI EPAFTPGPNI ELQKDSDCCS
70 80 90 100 110 120
CQEKWVGYRC NCYFISSEQK TWNESRHLCA SQKSSLLQLQ NTDELDFMSS SQQFYWIGLS
130 140 150 160 170
YSEEHTAWLW ENGSALSQYL FPSFETFNTK NCIAYNPNGN ALDESCEDKN RYICKQQLI
CATM prediction
The sequence of KLRD1_HUMAN returned 3 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 10 20 30 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LWRLISGTLGIICLSLMSTLGILLKNS | 7.1 | -51.1° | 2.4 | 44.7 | -30.4 |
| Model 2 | LWRLISGTLGIICLSLMSTLGILLKNS | 7.0 | -49.2° | 3.9 | 37.9 | -18.1 |
| Model 3 | LWRLISGTLGIICLSLMSTLGILLKNS | 7.4 | -45.0° | 4.0 | 39.0 | -11.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 25, SER, HA | A, 24, MET, O | 3.30Å |
| B, 28, GLY, HA1 | A, 25, SER, O | 3.05Å |
| A, 25, SER, HA | B, 24, MET, O | 3.30Å |
| A, 28, GLY, HA1 | B, 25, SER, O | 3.05Å |
