UniProt data
UniProt name: FA69C_HUMAN (Q0P6D2)
Gene name: FAM69C; Synonyms=C18orf51
Organism: Homo sapiens (Human).
Function:
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Transmembrane domains:
- 23-43, 21 AA, Helical. {ECO:0000255}.
Sequence: 419 AA
10 20 30 40 50 60
MARAAGARGP AGWCRRRGRC GRGTLLAFAA WTAGWVLAAA LLLRAHPGVL SERCTDEKSR
70 80 90 100 110 120
RILAALCQDY QGGTLAGDLC EDLCVAGELL FQRCLHYNRG KKVLQADWRG RPVVLKSKEE
130 140 150 160 170 180
AFSSFPPLSL LEEEAGEGGQ DMPEAELLLM VAGEVKSALG LELSNSSLGP WWPGRRGPRW
190 200 210 220 230 240
RGQLASLWAL LQQEEYVYFS LLQDLSPHVL PVLGSCGHFY AVEFLAAGSP HHRALFPLDR
250 260 270 280 290 300
APGAPGGGQA KAISDIALSF LDMVNHFDSD FSHRLHLCDI KPENFAIRSD FTVVAIDVDM
310 320 330 340 350 360
AFFEPKMREI LEQNCTGDED CNFFDCFSRC DLRVNKCGAQ RVNNNLQVIC DKIFRHWFSA
370 380 390 400 410
PLKSSAVSFQ LQLQLQEAVQ ECADPGVPSG NTRRAASSVF WKLRQLLQAT LRELQEAEK
CATM prediction
The sequence of FA69C_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 20 30 40 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | CGRGTLLAFAAWTAGWVLAAALLLRAH | 7.3 | -29.0° | 2.5 | 37.0 | -19.0 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 27, ALA, HA | A, 26, LEU, O | 3.49Å |
| B, 31, TRP, HA | A, 30, ALA, O | 3.33Å |
| A, 27, ALA, HA | B, 26, LEU, O | 3.49Å |
| A, 31, TRP, HA | B, 30, ALA, O | 3.32Å |