UniProt data
UniProt name: CQ074_HUMAN (Q0P670)
Gene name: C17orf74
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 26-46, 21 AA, Helical. {ECO:0000255}.
Sequence: 501 AA
10 20 30 40 50 60
MENQLWHNTV RCCNQYQESP HDAEDILLLL LGLIVLVNIG INVATMMWHG LQNALDKMID
70 80 90 100 110 120
WATQKNEIQA SESPPSGPPD KAQDVHIHCI LDPVQVKMSR PTQYSSFSCH HFSNHHSSSL
130 140 150 160 170 180
LRCVRRRRRR HRRCRRRCCN HQQRPQNYRQ IPHSHSVFRN PHRSQKMSQL HRVPFFDQED
190 200 210 220 230 240
PDSYLEEEDN LPFPYPKYPR RGWGGFYQRA GLPSNVGLWG HQGGILASLP PPSLYLSPEL
250 260 270 280 290 300
RCMPKRVEAR SELRLQSYGR HGSQSRLWGN VEAEQWASSP PPPHRLPPNP SWVPVGHSPY
310 320 330 340 350 360
PSVGWMLYDS WDQRRRGTEG FERPPASVSR NARPEAQGCR EHHSPQSHQQ SLLGHAYGQS
370 380 390 400 410 420
HRSPHPSTEP LGYSSQDPRE VRRRAADWAE ALPAWRPLTT SASLTVLDEA SHQRTPAPSS
430 440 450 460 470 480
VLVPHSSQPW PKVQAADPAP PPTMFVPLSR NPGGNANYQV YDSLELKRQV QKSRARSSSL
490 500
PPASTSTLRP SLHRSQTEKL N
CATM prediction
The sequence of CQ074_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 30 40 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | AEDILLLLLGLIVLVNIGINVATMMWH | 7.2 | -54.7° | 0.9 | 50.3 | -15.3 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 40, GLY, HA1 | A, 37, VAL, O | 3.17Å |
| B, 41, ILE, HA | A, 40, GLY, O | 3.28Å |
| A, 40, GLY, HA1 | B, 37, VAL, O | 3.17Å |
| A, 41, ILE, HA | B, 40, GLY, O | 3.28Å |