UniProt data
UniProt name: DLK1_HUMAN (P80370)
Gene name: DLK1; Synonyms=DLK
Organism: Homo sapiens (Human).
Function: May have a role in neuroendocrine differentiation.
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 304-327, 24 AA, Helical. {ECO:0000255}.
Sequence: 383 AA
10 20 30 40 50 60
MTATEALLRV LLLLLAFGHS TYGAECFPAC NPQNGFCEDD NVCRCQPGWQ GPLCDQCVTS
70 80 90 100 110 120
PGCLHGLCGE PGQCICTDGW DGELCDRDVR ACSSAPCANN RTCVSLDDGL YECSCAPGYS
130 140 150 160 170 180
GKDCQKKDGP CVINGSPCQH GGTCVDDEGR ASHASCLCPP GFSGNFCEIV ANSCTPNPCE
190 200 210 220 230 240
NDGVCTDIGG DFRCRCPAGF IDKTCSRPVT NCASSPCQNG GTCLQHTQVS YECLCKPEFT
250 260 270 280 290 300
GLTCVKKRAL SPQQVTRLPS GYGLAYRLTP GVHELPVQQP EHRILKVSMK ELNKKTPLLT
310 320 330 340 350 360
EGQAICFTIL GVLTSLVVLG TVGIVFLNKC ETWVSNLRYN HMLRKKKNLL LQYNSGEDLA
370 380
VNIIFPEKID MTTFSKEAGD EEI
CATM prediction
The sequence of DLK1_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 310 320 3 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | EGQAICFTILGVLTSLVVLGTVGIVFLNKC | 7.1 | -55.1° | 2.4 | 47.7 | -20.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 308, THR, HA | A, 307, PHE, O | 3.12Å |
| B, 311, GLY, HA1 | A, 308, THR, O | 2.93Å |
| B, 312, VAL, HA | A, 315, SER, OG | 3.19Å |
| B, 315, SER, HG1 | A, 315, SER, OG | 1.95Å |
| A, 308, THR, HA | B, 307, PHE, O | 3.12Å |
| A, 311, GLY, HA1 | B, 308, THR, O | 2.93Å |
| A, 312, VAL, HA | B, 315, SER, OG | 3.45Å |