UniProt data
UniProt name: EVA1C_HUMAN (P58658)
Gene name: EVA1C; Synonyms=C21orf63, C21orf64, FAM176C
Organism: Homo sapiens (Human).
Function: Binds heparin. {ECO:0000269|PubMed:19470522}.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 323-343, 21 AA, Helical. {ECO:0000255}.
Sequence: 441 AA
10 20 30 40 50 60
MLLPGRARQP PTPQPVQHPG LRRQVEPPGQ LLRLFYCTVL VCSKEISALT DFSGYLTKLL
70 80 90 100 110 120
QNHTTYACDG DYLNLQCPRH STISVQSAFY GQDYQMCSSQ KPASQREDSL TCVAATTFQK
130 140 150 160 170 180
VLDECQNQRA CHLLVNSRVF GPDLCPGSSK YLLVSFKCQP NELKNKTVCE DQELKLHCHE
190 200 210 220 230 240
SKFLNIYSAT YGRRTQERDI CSSKAERLPP FDCLSYSALQ VLSRRCYGKQ RCKIIVNNHH
250 260 270 280 290 300
FGSPCLPGVK KYLTVTYACV PKNILTAIDP AIANLKPSLK QKDGEYGINF DPSGSKVLRK
310 320 330 340 350 360
DGILVSNSLA AFAYIRAHPE RAALLFVSSV CIGLALTLCA LVIRESCAKD FRDLQLGREQ
370 380 390 400 410 420
LVPGSDKVEE DSEDEEEEED PSESDFPGEL SGFCRTSYPI YSSIEAAELA ERIERREQII
430 440
QEIWMNSGLD TSLPRNMGQF Y
CATM prediction
The sequence of EVA1C_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 320 330 340 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | ERAALLFVSSVCIGLALTLCALVIRES | 7.2 | -51.0° | 3.3 | 48.0 | -12.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 326, PHE, HA | A, 329, SER, OG | 3.30Å |
| B, 330, VAL, HA | A, 329, SER, O | 3.22Å |
| B, 333, GLY, HA1 | A, 330, VAL, O | 3.24Å |
| B, 334, LEU, HA | A, 337, THR, OG1 | 2.79Å |
| A, 326, PHE, HA | B, 329, SER, OG | 3.30Å |
| A, 330, VAL, HA | B, 329, SER, O | 3.22Å |
| A, 333, GLY, HA1 | B, 330, VAL, O | 3.24Å |
| A, 334, LEU, HA | B, 337, THR, OG1 | 2.79Å |