Ephrin-B2

UniProt data

UniProt name: EFNB2_HUMAN (P52799)

Gene name: EFNB2; Synonyms=EPLG5, HTKL, LERK5

Organism: Homo sapiens (Human).

Function: (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus. {ECO:0000269|PubMed:15998730, ECO:0000269|PubMed:16007075, ECO:0000269|PubMed:16477309, ECO:0000269|PubMed:17376907}.

Subcellular location: Membrane; Single-pass type I membrane protein.

Transmembrane domains:

  1. 230-250, 21 AA, Helical. {ECO:0000255}.

Sequence: 333 AA

10 20 30 40 50 60 MAVRRDSVWK YCWGVLMVLC RTAISKSIVL EPIYWNSSNS KFLPGQGLVL YPQIGDKLDI 70 80 90 100 110 120 ICPKVDSKTV GQYEYYKVYM VDKDQADRCT IKKENTPLLN CAKPDQDIKF TIKFQEFSPN 130 140 150 160 170 180 LWGLEFQKNK DYYIISTSNG SLEGLDNQEG GVCQTRAMKI LMKVGQDASS AGSTRNKDPT 190 200 210 220 230 240 RRPELEAGTN GRSSTTSPFV KPNPGSSTDG NSAGHSGNNI LGSEVALFAG IASGCIIFIV 250 260 270 280 290 300 IIITLVVLLL KYRRRHRKHS PQHTTTLSLS TLATPKRSGN NNGSEPSDII IPLRTADSVF 310 320 330 CPHYEKVSGD YGHPVYIVQE MPPQSPANIY YKV

CATM prediction

The sequence of EFNB2_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     230       240       250 
   |    +    |    +    |   		 (Å) (°) (Å) (°)  
Model 1 LFAGIASGCIIFIVIIITLVVLLLKYR 6.9 -54.0° 3.5 49.4 -22.5

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 231, ILE, HA A, 230, GLY, O 2.87Å
B, 234, GLY, HA1 A, 231, ILE, O 3.01Å
A, 231, ILE, HA B, 230, GLY, O 2.87Å
A, 234, GLY, HA1 B, 231, ILE, O 3.01Å