Translocon-associated protein subunit delta

UniProt data

UniProt name: SSRD_HUMAN (P51571)

Gene name: SSR4; Synonyms=TRAPD

Organism: Homo sapiens (Human).

Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Transmembrane domains:

  1. 145-165, 21 AA, Helical. {ECO:0000255}.

Sequence: 173 AA

10 20 30 40 50 60 MAAMASLGAL ALLLLSSLSR CSAEACLEPQ ITPSYYTTSD AVISTETVFI VEISLTCKNR 70 80 90 100 110 120 VQNMALYADV GGKQFPVTRG QDVGRYQVSW SLDHKSAHAG TYEVRFFDEE SYSLLRKAQR 130 140 150 160 170 NNEDISIIPP LFTVSVDHRG TWNGPWVSTE VLAAAIGLVI YYLAFSAKSH IQA

CATM prediction

The sequence of SSRD_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
          150       160      
   +    |    +    |    +   		 (Å) (°) (Å) (°)  
Model 1 WNGAWVSTEVLAAAIGLVIYYLAFSAK 7.0 -48.0° 4.4 34.8 -27.7
Prolines* WNGPWVSTEVLAAAIGLVIYYLAFSAK          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 146, TRP, HE1 A, 149, THR, OG1 2.28Å
B, 154, ALA, HA A, 153, ALA, O 3.04Å
B, 157, GLY, HA1 A, 154, ALA, O 3.25Å
A, 146, TRP, HE1 B, 149, THR, OG1 2.28Å
A, 154, ALA, HA B, 153, ALA, O 3.04Å
A, 157, GLY, HA1 B, 154, ALA, O 3.25Å