UniProt data
UniProt name: EVI2B_HUMAN (P34910)
Gene name: EVI2B; Synonyms=EVDB
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 203-226, 24 AA, Helical. {ECO:0000255}.
Sequence: 448 AA
10 20 30 40 50 60
MDPKYFILIL FCGHLNNTFF SKTETITTEK QSQPTLFTSS MSQVLANSQN TTGNPLGQPT
70 80 90 100 110 120
QFSDTFSGQS ISPAKVTAGQ PTPAVYTSSE KPEAHTSAGQ PLAYNTKQPT PIANTSSQQA
130 140 150 160 170 180
VFTSARQLPS ARTSTTQPPK SFVYTFTQQS SSVQIPSRKQ ITVHNPSTQP TSTVKNSPRS
190 200 210 220 230 240
TPGFILDTTS NKQTPQKNNY NSIAAILIGV LLTSMLVAII IIVLWKCLRK PVLNDQNWAG
250 260 270 280 290 300
RSPFADGETP DICMDNIREN EISTKRTSII SLTPWKPSKS TLLADDLEIK LFESSENIED
310 320 330 340 350 360
SNNPKTEKIK DQVNGTSEDS ADGSTVGTAV SSSDDADLPP PPPLLDLEGQ ESNQSDKPTM
370 380 390 400 410 420
TIVSPLPNDS TSLPPSLDCL NQDCGDHKSE IIQSFPPLDS LNLPLPPVDF MKNQEDSNLE
430 440
IQCQEFSIPP NSDQDLNESL PPPPAELL
CATM prediction
The sequence of EVI2B_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 200 210 220 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | YNSIAAILIGVLLTSMLVAIIIIVLWKCLR | 7.2 | -51.0° | 3.3 | 48.1 | -23.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 206, ILE, HA | A, 205, ALA, O | 3.20Å |
| B, 209, GLY, HA1 | A, 206, ILE, O | 3.21Å |
| B, 210, VAL, HA | A, 213, THR, OG1 | 2.86Å |
| A, 206, ILE, HA | B, 205, ALA, O | 3.20Å |
| A, 209, GLY, HA1 | B, 206, ILE, O | 3.21Å |
| A, 210, VAL, HA | B, 213, THR, OG1 | 2.86Å |