UniProt data
UniProt name: CD27_HUMAN (P26842)
Gene name: CD27; Synonyms=TNFRSF7
Organism: Homo sapiens (Human).
Function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 192-212, 21 AA, Helical. {ECO:0000255}.
Sequence: 260 AA
10 20 30 40 50 60
MARPHPWWLC VLGTLVGLSA TPAPKSCPER HYWAQGKLCC QMCEPGTFLV KDCDQHRKAA
70 80 90 100 110 120
QCDPCIPGVS FSPDHHTRPH CESCRHCNSG LLVRNCTITA NAECACRNGW QCRDKECTEC
130 140 150 160 170 180
DPLPNPSLTA RSSQALSPHP QPTHLPYVSE MLEARTAGHM QTLADFRQLP ARTLSTHWPP
190 200 210 220 230 240
QRSLCSSDFI RILVIFSGMF LVFTLAGALF LHQRRKYRSN KGESPVEPAE PCHYSCPREE
250
EGSTIPIQED YRKPEPACSP
CATM prediction
The sequence of CD27_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 190 200 210 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | FIRILVIFSGMFLVFTLAGALFLHQRR | 7.3 | -53.0° | 3.1 | 34.3 | -3.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 204, THR, HA | A, 203, PHE, O | 3.48Å |
| B, 207, GLY, HA1 | A, 204, THR, O | 3.31Å |
| A, 204, THR, HA | B, 203, PHE, O | 3.48Å |
| A, 207, GLY, HA1 | B, 204, THR, O | 3.31Å |