Cytochrome c oxidase subunit 7A1, mitochondrial

UniProt data

UniProt name: CX7A1_HUMAN (P24310)

Gene name: COX7A1; Synonyms=COX7AH

Organism: Homo sapiens (Human).

Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular location: Mitochondrion inner membrane.

Transmembrane domains:

  1. 47-75, 29 AA, Helical. {ECO:0000250}.

Sequence: 79 AA

10 20 30 40 50 60 MQALRVSQAL IRSFSSTARN RFQNRVREKQ KLFQEDNDIP LYLKGGIVDN ILYRVTMTLC 70 LGGTVYSLYS LGWASFPRN

CATM prediction

The sequence of CX7A1_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
        50        60        70       
 +    |    +    |    +    |    +   
(Å) (°) (Å) (°)  
KGGIVDNILYRVTMTLCLGGTVYSLYSLGWASFAR 6.8 -55.1° 1.5 44.9 -12.5
KGGIVDNILYRVTMTLCLGGTVYSLYSLGWASFPR          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 59, LEU, HA A, 58, THR, O 3.32Å
B, 62, GLY, HA1 A, 59, LEU, O 2.76Å
B, 63, GLY, HA2 A, 62, GLY, O 3.29Å
B, 67, SER, HG1 A, 66, TYR, OH 2.05Å
A, 59, LEU, HA B, 58, THR, O 3.32Å
A, 62, GLY, HA1 B, 59, LEU, O 2.76Å
A, 63, GLY, HA2 B, 62, GLY, O 3.29Å
A, 67, SER, HG1 B, 66, TYR, OH 2.05Å