Vesicle-associated membrane protein 1

UniProt data

UniProt name: VAMP1_HUMAN (P23763)

Gene name: VAMP1; Synonyms=SYB1

Organism: Homo sapiens (Human).

Function: Involved in the targeting and/or fusion of transport vesicles to their target membrane.

Subcellular location: Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein.

Transmembrane domains:

  1. 97-116, 20 AA, Helical; Anchor for type IV membrane protein. {ECO:0000255}.

Sequence: 118 AA

10 20 30 40 50 60 MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQ VEEVVDIIRV NVDKVLERDQ 70 80 90 100 110 KLSELDDRAD ALQAGASQFE SSAAKLKRKY WWKNCKMMIM LGAICAIIVV VIVIYFFT

CATM prediction

The sequence of VAMP1_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
        100       110      
 +    |    +    |    +   
(Å) (°) (Å) (°)  
NCKMMIMLGAICAIIVVVIVIYFFT 6.9 -47.0° 2.2 44.8 -27.7

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 99, ILE, HA A, 98, MET, O 3.05Å
B, 102, GLY, HA1 A, 99, ILE, O 2.78Å
B, 103, ALA, HA A, 102, GLY, O 3.14Å
A, 99, ILE, HA B, 98, MET, O 3.05Å
A, 102, GLY, HA1 B, 99, ILE, O 2.78Å
A, 103, ALA, HA B, 102, GLY, O 3.14Å