UniProt data
UniProt name: CD72_HUMAN (P21854)
Gene name: CD72
Organism: Homo sapiens (Human).
Function: Plays a role in B-cell proliferation and differentiation.
Subcellular location: Membrane; Single-pass type II membrane protein.
Transmembrane domains:
- 96-116, 21 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 359 AA
10 20 30 40 50 60
MAEAITYADL RFVKAPLKKS ISSRLGQDPG ADDDGEITYE NVQVPAVLGV PSSLASSVLG
70 80 90 100 110 120
DKAAVKSEQP TASWRAVTSP AVGRILPCRT TCLRYLLLGL LLTCLLLGVT AICLGVRYLQ
130 140 150 160 170 180
VSQQLQQTNR VLEVTNSSLR QQLRLKITQL GQSAEDLQGS RRELAQSQEA LQVEQRAHQA
190 200 210 220 230 240
AEGQLQACQA DRQKTKETLQ SEEQQRRALE QKLSNMENRL KPFFTCGSAD TCCPSGWIMH
250 260 270 280 290 300
QKSCFYISLT SKNWQESQKQ CETLSSKLAT FSEIYPQSHS YYFLNSLLPN GGSGNSYWTG
310 320 330 340 350
LSSNKDWKLT DDTQRTRTYA QSSKCNKVHK TWSWWTLESE SCRSSLPYIC EMTAFRFPD
CATM prediction
The sequence of CD72_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 100 110 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LRYLLLGLLLTCLLLGVTAICLGVRYL | 7.1 | -43.8° | 5.0 | 43.8 | -19.6 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 99, GLY, HA1 | A, 96, LEU, O | 3.43Å |
| B, 103, THR, HG1 | A, 103, THR, OG1 | 2.34Å |
| A, 99, GLY, HA1 | B, 96, LEU, O | 3.43Å |
| A, 100, LEU, HA | B, 103, THR, OG1 | 3.18Å |