Cytochrome c oxidase subunit 7C, mitochondrial

UniProt data

UniProt name: COX7C_HUMAN (P15954)

Gene name: COX7C

Organism: Homo sapiens (Human).

Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular location: Mitochondrion inner membrane {ECO:0000250}.

Transmembrane domains:

  1. 34-60, 27 AA, Helical. {ECO:0000250}.

Sequence: 63 AA

10 20 30 40 50 60 MLGQSIRRFT TSVVRRSHYE EGPGKNLPFS VENKWSLLAK MCLYFGSAFA TPFLVVRHQL LKT

CATM prediction

The sequence of COX7C_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
           40        50        60  
    +    |    +    |    +    |   
(Å) (°) (Å) (°)  
VENKWSLLAKMCLYFGSAFATAFLVVRHQLLKT 7.4 -45.8° 2.7 47.0 -6.6
VENKWSLLAKMCLYFGSAFATPFLVVRHQLLKT          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 43, LEU, HA A, 42, CYS, O 3.38Å
B, 46, GLY, HA1 A, 43, LEU, O 3.37Å
A, 43, LEU, HA B, 42, CYS, O 3.38Å
A, 46, GLY, HA1 B, 43, LEU, O 3.37Å