UniProt data
UniProt name: SIM17_HUMAN (P0DL12)
Gene name: SMIM17
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 96-116, 21 AA, Helical. {ECO:0000255}.
Sequence: 118 AA
10 20 30 40 50 60
MQSLRPEQTR GLLEPERTKT LLPRESRAWE KPPHPACTKD WEAVEVGASS HDSDEKDLSS
70 80 90 100 110
QETGLSQEWS SVEEDDESEG SQGFVEWSKA PQQTTIVLVV CVLFLFLVLT GMPMMFHI
CATM prediction
The sequence of SIM17_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 100 110 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | QTTIVLVVCVLFLFLVLTGMAMMFHI | 6.9 | -50.9° | 1.2 | 45.3 | -25.0 |
| Prolines* | QTTIVLVVCVLFLFLVLTGMPMMFHI |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 108, VAL, HA | A, 107, LEU, O | 3.44Å |
| B, 111, GLY, HA1 | A, 108, VAL, O | 2.92Å |
| B, 112, MET, HA | A, 111, GLY, O | 3.20Å |
| A, 108, VAL, HA | B, 107, LEU, O | 3.44Å |
| A, 111, GLY, HA1 | B, 108, VAL, O | 2.92Å |
| A, 112, MET, HA | B, 111, GLY, O | 3.20Å |