UniProt data
UniProt name: LIGO3_HUMAN (P0C6S8)
Gene name: LINGO3; Synonyms=LERN2, LRRN6B
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 532-552, 21 AA, Helical. {ECO:0000255}.
Sequence: 592 AA
10 20 30 40 50 60
MTCWLCVLSL PLLLLPAAPP PAGGCPARCE CTVQTRAVAC TRRRLTAVPD GIPAETRLLE
70 80 90 100 110 120
LSRNRIRCLN PGDLAALPAL EELDLSENAI AHVEPGAFAN LPRLRVLRLR GNQLKLIPPG
130 140 150 160 170 180
VFTRLDNLTL LDLSENKLVI LLDYTFQDLH SLRRLEVGDN DLVFVSRRAF AGLLALEELT
190 200 210 220 230 240
LERCNLTALS GESLGHLRSL GALRLRHLAI ASLEDQNFRR LPGLLHLEID NWPLLEEVAA
250 260 270 280 290 300
GSLRGLNLTS LSVTHTNITA VPAAALRHQA HLTCLNLSHN PISTVPRGSF RDLVRLRELH
310 320 330 340 350 360
LAGALLAVVE PQAFLGLRQI RLLNLSNNLL STLEESTFHS VNTLETLRVD GNPLACDCRL
370 380 390 400 410 420
LWIVQRRKTL NFDGRLPACA TPAEVRGDAL RNLPDSVLFE YFVCRKPKIR ERRLQRVTAT
430 440 450 460 470 480
AGEDVRFLCR AEGEPAPTVA WVTPQHRPVT ATSAGRARVL PGGTLEIQDA RPQDSGTYTC
490 500 510 520 530 540
VASNAGGNDT YFATLTVRPE PAANRTPGEA HNETLAALRA PLDLTTILVS TAMGCITFLG
550 560 570 580 590
VVLFCFVLLF VWSRGRGQHK NNFSVEYSFR KVDGPAAAAG QGGARKFNMK MI
CATM prediction
The sequence of LIGO3_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 530 540 550 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | VSTAMGCITFLGVVLFCFVLLFVWSRG | 7.0 | -51.0° | 2.4 | 45.0 | -12.7 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session