UniProt data
UniProt name: CD7_HUMAN (P09564)
Gene name: CD7
Organism: Homo sapiens (Human).
Function: Not yet known.
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 181-201, 21 AA, Helical. {ECO:0000305}.
Sequence: 240 AA
10 20 30 40 50 60
MAGPPRLLLL PLLLALARGL PGALAAQEVQ QSPHCTTVPV GASVNITCST SGGLRGIYLR
70 80 90 100 110 120
QLGPQPQDII YYEDGVVPTT DRRFRGRIDF SGSQDNLTIT MHRLQLSDTG TYTCQAITEV
130 140 150 160 170 180
NVYGSGTLVL VTEEQSQGWH RCSDAPPRAS ALPAPPTGSA LPDPQTASAL PDPPAASALP
190 200 210 220 230
AALAVISFLL GLGLGVACVL ARTQIKKLCS WRDKNSAACV VYEDMSHSRC NTLSSPNQYQ
CATM prediction
The sequence of CD7_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 180 190 200 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | ALAAALAVISFLLGLGLGVACVLARTQ | 6.6 | -48.0° | 0.7 | 54.2 | -9.9 |
| Model 2 | ALAAALAVISFLLGLGLGVACVLARTQ | 6.9 | -23.0° | 4.2 | 54.0 | -7.4 |
| Prolines* | ALPAALAVISFLLGLGLGVACVLARTQ |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 188, PHE, HA | A, 187, SER, O | 3.25Å |
| B, 191, GLY, HA1 | A, 188, PHE, O | 2.81Å |
| B, 192, LEU, HA | A, 191, GLY, O | 2.80Å |
| A, 188, PHE, HA | B, 187, SER, O | 3.25Å |
| A, 191, GLY, HA1 | B, 188, PHE, O | 2.81Å |
| A, 192, LEU, HA | B, 191, GLY, O | 2.80Å |
