Glycophorin-B

UniProt data

UniProt name: GLPB_HUMAN (P06028)

Gene name: GYPB; Synonyms=GPB

Organism: Homo sapiens (Human).

Function: This protein is a minor sialoglycoprotein in erythrocyte membranes.

Subcellular location: Cell membrane; Single-pass type I membrane protein.

Transmembrane domains:

  1. 60-81, 22 AA, Helical. {ECO:0000255}.

Sequence: 91 AA

10 20 30 40 50 60 MYGKIIFVLL LSEIVSISAL STTEVAMHTS TSSSVTKSYI SSQTNGETGQ LVHRFTVPAP 70 80 90 VVIILIILCV MAGIIGTILL ISYSIRRLIK A

CATM prediction

The sequence of GLPB_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     60        70        80   
   |    +    |    +    |    
(Å) (°) (Å) (°)  
VAAAVVIILIILCVMAGIIGTILLISYS 7.3 -53.8° 2.9 51.0 -22.2
VAAAVVIILIILCVMAGIIGTILLISYS 6.8 -54.9° 4.2 37.9 -14.9
VPAPVVIILIILCVMAGIIGTILLISYS          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 70, VAL, HA A, 69, CYS, O 3.39Å
B, 73, GLY, HA1 A, 70, VAL, O 3.31Å
B, 74, ILE, HA A, 77, THR, OG1 2.87Å
A, 70, VAL, HA B, 69, CYS, O 3.39Å
A, 73, GLY, HA1 B, 70, VAL, O 3.31Å
A, 74, ILE, HA B, 77, THR, OG1 2.87Å