UniProt data
UniProt name: AT1B1_HUMAN (P05026)
Gene name: ATP1B1; Synonyms=ATP1B
Organism: Homo sapiens (Human).
Function: Involved in cell adhesion and establishing epithelial cell polarity. {ECO:0000269|PubMed:19694409}.
Subcellular location: Cell membrane; Single-pass type II membrane protein.
Transmembrane domains:
- 35-62, 28 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 303 AA
10 20 30 40 50 60
MARGKAKEEG SWKKFIWNSE KKEFLGRTGG SWFKILLFYV IFYGCLAGIF IGTIQVMLLT
70 80 90 100 110 120
ISEFKPTYQD RVAPPGLTQI PQIQKTEISF RPNDPKSYEA YVLNIVRFLE KYKDSAQRDD
130 140 150 160 170 180
MIFEDCGDVP SEPKERGDFN HERGERKVCR FKLEWLGNCS GLNDETYGYK EGKPCIIIKL
190 200 210 220 230 240
NRVLGFKPKP PKNESLETYP VMKYNPNVLP VQCTGKRDED KDKVGNVEYF GLGNSPGFPL
250 260 270 280 290 300
QYYPYYGKLL QPKYLQPLLA VQFTNLTMDT EIRIECKAYG ENIGYSEKDR FQGRFDVKIE
VKS
CATM prediction
The sequence of AT1B1_HUMAN returned 4 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 40 50 60 + | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | WFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFK | 6.5 | -51.0° | 3.3 | 48.2 | -29.8 |
| Model 2 | WFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFK | 6.4 | -44.9° | 4.4 | 54.9 | -27.3 |
| Model 3 | WFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFK | 6.6 | -55.0° | 5.0 | 52.8 | -12.7 |
| Model 4 | WFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFK | 7.1 | -54.9° | 0.9 | 50.1 | -10.1 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 45, CYS, HA | A, 44, GLY, O | 2.92Å |
| B, 48, GLY, HA1 | A, 45, CYS, O | 2.56Å |
| B, 49, ILE, HA | A, 48, GLY, O | 2.92Å |
| A, 45, CYS, HA | B, 44, GLY, O | 2.92Å |
| A, 48, GLY, HA1 | B, 45, CYS, O | 2.56Å |
| A, 49, ILE, HA | B, 48, GLY, O | 2.92Å |
