UniProt data
UniProt name: IGSF6_HUMAN (O95976)
Gene name: IGSF6; Synonyms=DORA
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 154-174, 21 AA, Helical. {ECO:0000255}.
Sequence: 241 AA
10 20 30 40 50 60
MGTASRSNIA RHLQTNLILF CVGAVGACTL SVTQPWYLEV DYTHEAVTIK CTFSATGCPS
70 80 90 100 110 120
EQPTCLWFRY GAHQPENLCL DGCKSEADKF TVREALKENQ VSLTVNRVTS NDSAIYICGI
130 140 150 160 170 180
AFPSVPEARA KQTGGGTTLV VREIKLLSKE LRSFLTALVS LLSVYVTGVC VAFILLSKSK
190 200 210 220 230 240
SNPLRNKEIK EDSQKKKSAR RIFQEIAQEL YHKRHVETNQ QSEKDNNTYE NRRVLSNYER
P
CATM prediction
The sequence of IGSF6_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 160 170 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LRSFLTALVSLLSVYVTGVCVAFILLS | 7.3 | -51.0° | 2.4 | 44.9 | -13.6 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 165, TYR, HA | A, 164, VAL, O | 3.43Å |
| B, 168, GLY, HA1 | A, 165, TYR, O | 3.23Å |
| A, 165, TYR, HA | B, 164, VAL, O | 3.43Å |
| A, 168, GLY, HA1 | B, 165, TYR, O | 3.23Å |