NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

UniProt data

UniProt name: NDUB4_HUMAN (O95168)

Gene name: NDUFB4

Organism: Homo sapiens (Human).

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.

Transmembrane domains:

  1. 88-105, 18 AA, Helical. {ECO:0000255}.

Sequence: 129 AA

10 20 30 40 50 60 MSFPKYKPSS LRTLPETLDP AEYNISPETR RAQAERLAIR AQLKREYLLQ YNDPNRRGLI 70 80 90 100 110 120 ENPALLRWAY ARTINVYPNF RPTPKNSLMG ALCGFGPLIF IYYIIKTERD RKEKLIQEGK LDRTFHLSY

CATM prediction

The sequence of NDUB4_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
       90        100      
+    |    +    |    +   		 (Å) (°) (Å) (°)  
Model 1 KNSLMGALCGFGALIFIYYIIKTE 7.0 -29.0° 4.7 52.0 -12.3
Prolines* KNSLMGALCGFGPLIFIYYIIKTE          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session