UniProt data
UniProt name: LRIG2_HUMAN (O94898)
Gene name: LRIG2; Synonyms=KIAA0806, LIG2
Organism: Homo sapiens (Human).
Function:
Subcellular location: Cell membrane {ECO:0000269|PubMed:15145052}; Single-pass type I membrane protein {ECO:0000269|PubMed:15145052}. Cytoplasm {ECO:0000269|PubMed:15145052}.
Transmembrane domains:
- 808-828, 21 AA, Helical. {ECO:0000255}.
Sequence: 1065 AA
10 20 30 40 50 60
MAPAPLGVPE EQLLGCRSRV LSRLLFIAQT ALLLLPAAGA GLCPAPCSCR IPLLDCSRRK
70 80 90 100 110 120
LPAPSWRALS GLLPPDTAIL DFSHNRLSNW NISLESQTLQ EVKMNYNELT EIPYFGEPTS
130 140 150 160 170 180
NITLLSLVHN IIPEINAQAL QFYPALESLD LSSNIISEIK TSSFPRMQLK YLNLSNNRIT
190 200 210 220 230 240
TLEAGCFDNL SSSLLVVKLN RNRMSMIPPK IFKLPHLQFL ELKRNRIKIV EGLTFQGLDS
250 260 270 280 290 300
LRSLKMQRNG ISKLKDGAFF GLNNMEELEL EHNNLTRVNK GWLYGLRMLQ QLYVSQNAIE
310 320 330 340 350 360
RISPDAWEFC QRLSELDLSY NQLTRLDESA FVGLSLLERL NLGDNRVTHI ADGVFRFLSN
370 380 390 400 410 420
LQTLDLRNNE ISWAIEDASE AFAGLTSLTK LILQGNQIKS ITKKAFIGLE SLEHLDLNNN
430 440 450 460 470 480
AIMSIQENAF SQTHLKELIL NTSSLLCDCH LKWLLQWLVD NNFQHSVNVS CAHPEWLAGQ
490 500 510 520 530 540
SILNVDLKDF VCDDFLKPQI RTHPETIIAL RGMNVTLTCT AVSSSDSPMS TVWRKDSEIL
550 560 570 580 590 600
YDVDTENFVR YWQQAGEALE YTSILHLFNV NFTDEGKYQC IVTNHFGSNY SQKAKLTVNE
610 620 630 640 650 660
MPSFLKTPMD LTIRTGAMAR LECAAEGHPA PQISWQKDGG TDFPAARERR MHVMPEDDVF
670 680 690 700 710 720
FIANVKIEDM GIYSCMAQNT AGGLSANASL TVLETPSFIR PLEDKTVTRG ETAVLQCIAG
730 740 750 760 770 780
GSPAPRLNWT KDDGPLLVTE RHFFAAANQL LIIVDAGLED AGKYTCIMSN TLGTERGHIY
790 800 810 820 830 840
LNVISSPNCD SSQSSIGHED DGWTTVGIVI IVVVCCVVGT SLIWVIVIYH MRRKNEDYSI
850 860 870 880 890 900
TNTEELNLPA DIPSYLSSQG TLSEPQEGYS NSEAGSHQQL MPPANGYIHK GTDGGTGTRV
910 920 930 940 950 960
ICSDCYDNAN IYSRTREYCP YTYIAEEDVL DQTLSSLMVQ MPKETYLVHP PQDTTALESL
970 980 990 1000 1010 1020
IPSANREPSA FPTNHERISE KKLPSTQMSG ETLQRPVWNI NRELGLPHPP FSQQPVHESP
1030 1040 1050 1060
QLHQNEGLAG REPDCSASSM SCHRLQDHAF DFSRTRNIQD GSEGT
CATM prediction
The sequence of LRIG2_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 810 820 83 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | TVGIVIIVVVCCVVGTSLIWVIVIYHM | 7.4 | -54.3° | 2.8 | 51.5 | -14.0 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 816, CYS, HA | A, 815, CYS, O | 3.45Å |
| B, 819, GLY, HA1 | A, 816, CYS, O | 3.43Å |
| A, 816, CYS, HA | B, 815, CYS, O | 3.45Å |
| A, 819, GLY, HA1 | B, 816, CYS, O | 3.43Å |