NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

UniProt data

UniProt name: NDUB1_HUMAN (O75438)

Gene name: NDUFB1

Organism: Homo sapiens (Human).

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.

Transmembrane domains:

  1. 11-27, 17 AA, Helical. {ECO:0000255}.

Sequence: 58 AA

10 20 30 40 50 MVNLLQIVRD HWVHVLVPMG FVIGCYLDRK SDERLTAFRN KSMLFKRELQ PSEEVTWK

CATM prediction

The sequence of NDUB1_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
    10        20        3
  |    +    |    +    |
(Å) (°) (Å) (°)  
VRDHWVHVLVAMGFVIGCYLDRK 7.4 -48.3° 0.4 47.3 -1.4
VRDHWVHVLVPMGFVIGCYLDRK          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 24, GLY, HA1 A, 21, PHE, O 3.30Å
B, 25, CYS, HA A, 24, GLY, O 3.34Å
A, 24, GLY, HA1 B, 21, PHE, O 3.30Å
A, 25, CYS, HA B, 24, GLY, O 3.34Å