UniProt data
UniProt name: LIRB5_HUMAN (O75023)
Gene name: LILRB5; Synonyms=LIR8
Organism: Homo sapiens (Human).
Function: May act as receptor for class I MHC antigens.
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 459-479, 21 AA, Helical. {ECO:0000255}.
Sequence: 590 AA
10 20 30 40 50 60
MTLTLSVLIC LGLSVGPRTC VQAGTLPKPT LWAEPASVIA RGKPVTLWCQ GPLETEEYRL
70 80 90 100 110 120
DKEGLPWARK RQNPLEPGAK AKFHIPSTVY DSAGRYRCYY ETPAGWSEPS DPLELVATGF
130 140 150 160 170 180
YAEPTLLALP SPVVASGGNV TLQCDTLDGL LTFVLVEEEQ KLPRTLYSQK LPKGPSQALF
190 200 210 220 230 240
PVGPVTPSCR WRFRCYYYYR KNPQVWSNPS DLLEILVPGV SRKPSLLIPQ GSVVARGGSL
250 260 270 280 290 300
TLQCRSDVGY DIFVLYKEGE HDLVQGSGQQ PQAGLSQANF TLGPVSRSHG GQYRCYGAHN
310 320 330 340 350 360
LSPRWSAPSD PLDILIAGLI PDIPALSVQP GPKVASGENV TLLCQSWHQI DTFFLTKEGA
370 380 390 400 410 420
AHPPLCLKSK YQSYRHQAEF SMSPVTSAQG GTYRCYSAIR SYPYLLSSPS YPQELVVSGP
430 440 450 460 470 480
SGDPSLSPTG STPTPGPEDQ PLTPTGLDPQ SGLGRHLGVV TGVSVAFVLL LFLLLFLLLR
490 500 510 520 530 540
HRHQSKHRTS AHFYRPAGAA GPEPKDQGLQ KRASPVADIQ EEILNAAVKD TQPKDGVEMD
550 560 570 580
ARAAASEAPQ DVTYAQLHSL TLRREATEPP PSQEREPPAE PSIYAPLAIH
CATM prediction
The sequence of LIRB5_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 460 470 480 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | HLGVVTGVSVAFVLLLFLLLFLLLRHR | 6.6 | -49.1° | 2.2 | 58.9 | -22.9 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 462, GLY, HA1 | A, 459, VAL, O | 2.41Å |
| B, 463, VAL, HA | A, 462, GLY, O | 3.25Å |
| A, 462, GLY, HA1 | B, 459, VAL, O | 2.41Å |
| A, 463, VAL, HA | B, 462, GLY, O | 3.25Å |