UniProt data
UniProt name: MPZL2_HUMAN (O60487)
Gene name: MPZL2; Synonyms=EVA, EVA1; ORFNames=UNQ606/PRO1192
Organism: Homo sapiens (Human).
Function: Mediates homophilic cell-cell adhesion.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 155-175, 21 AA, Helical. {ECO:0000255}.
Sequence: 215 AA
10 20 30 40 50 60
MYGKSSTRAV LLLLGIQLTA LWPIAAVEIY TSRVLEAVNG TDARLKCTFS SFAPVGDALT
70 80 90 100 110 120
VTWNFRPLDG GPEQFVFYYH IDPFQPMSGR FKDRVSWDGN PERYDASILL WKLQFDDNGT
130 140 150 160 170 180
YTCQVKNPPD VDGVIGEIRL SVVHTVRFSE IHFLALAIGS ACALMIIIVI VVVLFQHYRK
190 200 210
KRWAERAHKV VEIKSKEEER LNQEKKVSVY LEDTD
CATM prediction
The sequence of MPZL2_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 160 170 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | HFLALAIGSACALMIIIVIVVVLFQHY | 6.7 | -44.1° | 1.8 | 45.0 | -27.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 156, LEU, HA | A, 155, ALA, O | 3.01Å |
| B, 159, GLY, HA1 | A, 156, LEU, O | 2.85Å |
| B, 160, SER, HA | A, 159, GLY, O | 3.32Å |
| A, 156, LEU, HA | B, 155, ALA, O | 3.01Å |
| A, 159, GLY, HA1 | B, 156, LEU, O | 2.85Å |
| A, 160, SER, HA | B, 159, GLY, O | 3.32Å |