UniProt data
UniProt name: TMG2_HUMAN (O14669)
Gene name: PRRG2; Synonyms=PRGP2, TMG2
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 110-132, 23 AA, Helical. {ECO:0000255}.
Sequence: 202 AA
10 20 30 40 50 60
MRGHPSLLLL YMALTTCLDT SPSEETDQEV FLGPPEAQSF LSSHTRIPRA NHWDLELLTP
70 80 90 100 110 120
GNLERECLEE RCSWEEAREY FEDNTLTERF WESYIYNGKG GRGRVDVASL AVGLTGGILL
130 140 150 160 170 180
IVLAGLGAFW YLRWRQHRGQ QPCPQEAGLI SPLSPLNPLG PPTPLPPPPP PPPGLPTYEQ
190 200
ALAASGVHDA PPPPYTSLRR PH
CATM prediction
The sequence of TMG2_HUMAN returned 6 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 110 120 130 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | VASLAVGLTGGILLIVLAGLGAFWYLRWR | 6.7 | -46.9° | 1.4 | 45.0 | -21.8 |
| Model 2 | VASLAVGLTGGILLIVLAGLGAFWYLRWR | 6.9 | -25.0° | 4.8 | 51.0 | -19.6 |
| Model 3 | VASLAVGLTGGILLIVLAGLGAFWYLRWR | 7.4 | -54.0° | 3.6 | 49.0 | -3.8 |
| Model 4 | VASLAVGLTGGILLIVLAGLGAFWYLRWR | 7.1 | +52.0° | 1.8 | 1.0 | -3.1 |
| Model 5 | VASLAVGLTGGILLIVLAGLGAFWYLRWR | 7.3 | -54.0° | 3.6 | 35.0 | -2.0 |
| Model 6 | VASLAVGLTGGILLIVLAGLGAFWYLRWR | 6.8 | -55.0° | 1.5 | 44.5 | -1.0 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 113, GLY, HA1 | A, 110, LEU, O | 2.72Å |
| B, 114, LEU, HA | A, 113, GLY, O | 2.91Å |
| A, 113, GLY, HA1 | B, 110, LEU, O | 2.72Å |
| A, 114, LEU, HA | B, 113, GLY, O | 2.91Å |
