Golgi SNAP receptor complex member 2

UniProt data

UniProt name: GOSR2_HUMAN (O14653)

Gene name: GOSR2; Synonyms=GS27

Organism: Homo sapiens (Human).

Function: Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network.

Subcellular location: Golgi apparatus, cis-Golgi network membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus (By similarity). {ECO:0000250}.

Transmembrane domains:

  1. 191-211, 21 AA, Helical; Anchor for type IV membrane protein. {ECO:0000255}.

Sequence: 212 AA

10 20 30 40 50 60 MDPLFQQTHK QVHEIQSCMG RLETADKQSV HIVENEIQAS IDQIFSRLER LEILSSKEPP 70 80 90 100 110 120 NKRQNARLRV DQLKYDVQHL QTALRNFQHR RHAREQQERQ REELLSRTFT TNDSDTTIPM 130 140 150 160 170 180 DESLQFNSSL QKVHNGMDDL ILDGHNILDG LRTQRLTLKG TQKKILDIAN MLGLSNTVMR 190 200 210 LIEKRAFQDK YFMIGGMLLT CVVMFLVVQY LT

CATM prediction

The sequence of GOSR2_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
    190       200       210
  |    +    |    +    |  		 (Å) (°) (Å) (°)  
Model 1 QDKYFMIGGMLLTCVVMFLVVQYLT 7.2 -40.7° 3.5 37.9 -27.4

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 193, MET, HA A, 192, PHE, O 3.18Å
B, 196, GLY, HA1 A, 193, MET, O 3.21Å
B, 197, MET, HA A, 200, THR, OG1 2.48Å
A, 193, MET, HA B, 192, PHE, O 3.18Å
A, 196, GLY, HA1 B, 193, MET, O 3.21Å
A, 197, MET, HA B, 200, THR, OG1 2.63Å