UniProt data
UniProt name: HRK_HUMAN (O00198)
Gene name: HRK; Synonyms=BID3
Organism: Homo sapiens (Human).
Function: Promotes apoptosis. {ECO:0000269|PubMed:15031724, ECO:0000269|PubMed:9130713}.
Subcellular location: Membrane; Single-pass membrane protein. Mitochondrion.
Transmembrane domains:
- 69-87, 19 AA, Helical. {ECO:0000255}.
Sequence: 91 AA
CATM prediction
The sequence of HRK_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 70 80 9 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | ATYWAWLCAAAQVAALAAWLLGRRN | 7.2 | -37.0° | 2.3 | 35.9 | -5.0 |
| Prolines* | PTYWPWLCAAAQVAALAAWLLGRRN |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 80, ALA, HA | A, 79, ALA, O | 3.46Å |
| B, 84, TRP, HA | A, 83, ALA, O | 3.38Å |
| A, 80, ALA, HA | B, 79, ALA, O | 3.46Å |
| A, 84, TRP, HA | B, 83, ALA, O | 3.38Å |