UniProt data
UniProt name: K132L_HUMAN (A8MWY0)
Gene name: KIAA1324L; Synonyms=EIG121L
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 930-950, 21 AA, Helical. {ECO:0000255}.
Sequence: 1029 AA
10 20 30 40 50 60
MLFRARGPVR GRGWGRPAEA PRRGRSPPWS PAWICCWALA GCQAAWAGDL PSSSSRPLPP
70 80 90 100 110 120
CQEKDYHFEY TECDSSGSRW RVAIPNSAVD CSGLPDPVRG KECTFSCASG EYLEMKNQVC
130 140 150 160 170 180
SKCGEGTYSL GSGIKFDEWD ELPAGFSNIA TFMDTVVGPS DSRPDGCNNS SWIPRGNYIE
190 200 210 220 230 240
SNRDDCTVSL IYAVHLKKSG YVFFEYQYVD NNIFFEFFIQ NDQCQEMDTT TDKWVKLTDN
250 260 270 280 290 300
GEWGSHSVML KSGTNILYWR TTGILMGSKA VKPVLVKNIT IEGVAYTSEC FPCKPGTFSN
310 320 330 340 350 360
KPGSFNCQVC PRNTYSEKGA KECIRCKDDS QFSEEGSSEC TERPPCTTKD YFQIHTPCDE
370 380 390 400 410 420
EGKTQIMYKW IEPKICREDL TDAIRLPPSG EKKDCPPCNP GFYNNGSSSC HPCPPGTFSD
430 440 450 460 470 480
GTKECRPCPA GTEPALGFEY KWWNVLPGNM KTSCFNVGNS KCDGMNGWEV AGDHIQSGAG
490 500 510 520 530 540
GSDNDYLILN LHIPGFKPPT SMTGATGSEL GRITFVFETL CSADCVLYFM VDINRKSTNV
550 560 570 580 590 600
VESWGGTKEK QAYTHIIFKN ATFTFTWAFQ RTNQGQDNRR FINDMVKIYS ITATNAVDGV
610 620 630 640 650 660
ASSCRACALG SEQSGSSCVP CPPGHYIEKE TNQCKECPPD TYLSIHQVYG KEACIPCGPG
670 680 690 700 710 720
SKNNQDHSVC YSDCFFYHEK ENQSLHYDFS NLSSVGSLMN GPSFTSKGTK YFHFFNISLC
730 740 750 760 770 780
GHEGKKMALC TNNITDFTVK EIVAGSDDYT NLVGAFVCQS TIIPSESKGF RAALSSQSII
790 800 810 820 830 840
LADTFIGVTV ETTLKNINIK EDMFPVPTSQ IPDVHFFYKS STATTSCING RSTAVKMRCN
850 860 870 880 890 900
PTKSGAGVIS VPSKCPAGTC DGCTFYFLWE SAEACPLCTE HDFHEIEGAC KRGFQETLYV
910 920 930 940 950 960
WNEPKWCIKG ISLPEKKLAT CETVDFWLKV GAGVGAFTAV LLVALTCYFW KKNQKLEYKY
970 980 990 1000 1010 1020
SKLVMTTNSK ECELPAADSC AIMEGEDNEE EVVYSNKQSL LGKLKSLATK EKEDHFESVQ
LKTSRSPNI
CATM prediction
The sequence of K132L_HUMAN returned 6 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 930 940 950 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | WLKVGAGVGAFTAVLLVALTCYFWKKN | 6.5 | -40.8° | 3.5 | 37.7 | -25.5 |
| Model 2 | WLKVGAGVGAFTAVLLVALTCYFWKKN | 7.1 | -26.0° | 3.6 | 54.0 | -22.7 |
| Model 3 | WLKVGAGVGAFTAVLLVALTCYFWKKN | 7.0 | -45.5° | 2.3 | 31.8 | -21.9 |
| Model 4 | WLKVGAGVGAFTAVLLVALTCYFWKKN | 6.4 | -50.6° | 4.8 | 56.9 | -11.7 |
| Model 5 | WLKVGAGVGAFTAVLLVALTCYFWKKN | 7.1 | -36.0° | 5.1 | 45.0 | -4.7 |
| Model 6 | WLKVGAGVGAFTAVLLVALTCYFWKKN | 6.9 | -55.0° | 1.5 | 44.5 | -3.3 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 932, ALA, HA | A, 931, GLY, O | 2.45Å |
| B, 935, GLY, HA1 | A, 932, ALA, O | 2.50Å |
| B, 936, ALA, HA | A, 935, GLY, O | 3.11Å |
| A, 932, ALA, HA | B, 931, GLY, O | 2.45Å |
| A, 935, GLY, HA1 | B, 932, ALA, O | 2.50Å |
| A, 936, ALA, HA | B, 935, GLY, O | 3.11Å |
