UniProt data
UniProt name: SMCO3_HUMAN (A2RU48)
Gene name: SMCO3; Synonyms=C12orf69
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 155-175, 21 AA, Helical. {ECO:0000255}.
Sequence: 225 AA
10 20 30 40 50 60
MAQSDFLYPE NPKRREEVNR LHQQLLDCLS DSFDVTNKLT EVLNMHLGCR LASIEMKRDG
70 80 90 100 110 120
TIKENCDLII QAIMKIQKEL QKVDEALKDK LEPTLYRKLQ DIKEKETDKI AIVQKVISVI
130 140 150 160 170 180
LGEATSAASA VAVKLVGSNV TTGIINKLVT VLAQIGASLL GSIGVAVLGL GIDMIVRAIL
190 200 210 220
GAVEKTQLQA AIKSYEKHLV EFKSASEKYN HAITEVINTV KHQMK
CATM prediction
The sequence of SMCO3_HUMAN returned 3 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 160 170 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LAQIGASLLGSIGVAVLGLGIDMIVRA | 7.1 | -45.9° | 4.7 | 37.9 | -24.4 |
| Model 2 | LAQIGASLLGSIGVAVLGLGIDMIVRA | 7.3 | -51.0° | 2.4 | 45.0 | -20.8 |
| Model 3 | LAQIGASLLGSIGVAVLGLGIDMIVRA | 7.1 | +52.2° | 1.8 | 1.2 | -11.3 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 158, SER, HA | A, 157, ALA, O | 3.13Å |
| B, 161, GLY, HA1 | A, 158, SER, O | 3.37Å |
| A, 158, SER, HA | B, 157, ALA, O | 3.13Å |
| A, 161, GLY, HA1 | B, 158, SER, O | 3.37Å |
