UniProt data
UniProt name: IGS23_HUMAN (A1L1A6)
Gene name: IGSF23
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 158-178, 21 AA, Helical. {ECO:0000255}.
Sequence: 192 AA
10 20 30 40 50 60
MRAKPQSPLP RNPVPAWSPP TTTTDPMLEK DAAGGDFPAN LVLQLMPLKT FPAAIRGVIQ
70 80 90 100 110 120
SELNYSVILQ WVVTMDPEPV LSWTFSGVPC GMGEKLFIRR LSCEQLGTYM CIATNSKKQL
130 140 150 160 170 180
VSEPVTISLP KPIMQPTEAE PMEPDPTLSL SGGSAIGLLA AGILGAGALI AGMCFIIIQS
190
LRTDRQRIGI CS
CATM prediction
The sequence of IGS23_HUMAN returned 4 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 160 170 18 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | AIGLLAAGILGAGALIAGMCFIIIQSL | 7.0 | -47.2° | 1.4 | 45.0 | -34.5 |
| Model 2 | AIGLLAAGILGAGALIAGMCFIIIQSL | 6.8 | -55.1° | 4.2 | 38.1 | -17.4 |
| Model 3 | AIGLLAAGILGAGALIAGMCFIIIQSL | 7.2 | -53.0° | 2.0 | 44.9 | -9.2 |
| Model 4 | AIGLLAAGILGAGALIAGMCFIIIQSL | 7.4 | -54.1° | 3.6 | 49.0 | -6.1 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 164, LEU, HA | A, 163, ILE, O | 3.36Å |
| B, 167, GLY, HA1 | A, 164, LEU, O | 2.97Å |
| B, 168, ALA, HA | A, 167, GLY, O | 3.21Å |
| A, 164, LEU, HA | B, 163, ILE, O | 3.36Å |
| A, 167, GLY, HA1 | B, 164, LEU, O | 2.97Å |
| A, 168, ALA, HA | B, 167, GLY, O | 3.21Å |
