UniProt data
UniProt name: ILVBL_HUMAN (A1L0T0)
Gene name: ILVBL; Synonyms=AHAS
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane; Single-pass membrane protein.
Transmembrane domains:
- 13-33, 21 AA, Helical. {ECO:0000255}.
Sequence: 632 AA
10 20 30 40 50 60
METPAAAAPA GSLFPSFLLL ACGTLVAALL GAAHRLGLFY QLLHKVDKAS VRHGGENVAA
70 80 90 100 110 120
VLRAHGVRFI FTLVGGHISP LLVACEKLGI RVVDTRHEVT AVFAADAMAR LSGTVGVAAV
130 140 150 160 170 180
TAGPGLTNTV TAVKNAQMAQ SPILLLGGAA STLLQNRGAL QAVDQLSLFR PLCKFCVSVR
190 200 210 220 230 240
RVRDIVPTLR AAMAAAQSGT PGPVFVELPV DVLYPYFMVQ KEMVPAKPPK GLVGRVVSWY
250 260 270 280 290 300
LENYLANLFA GAWEPQPEGP LPLDIPQASP QQVQRCVEIL SRAKRPLMVL GSQALLTPTS
310 320 330 340 350 360
ADKLRAAVET LGVPCFLGGM ARGLLGRNHP LHIRENRSAA LKKADVIVLA GTVCDFRLSY
370 380 390 400 410 420
GRVLSHSSKI IIVNRNREEM LLNSDIFWKP QEAVQGDVGS FVLKLVEGLQ GQTWAPDWVE
430 440 450 460 470 480
ELREADRQKE QTFREKAAMP VAQHLNPVQV LQLVEETLPD NSILVVDGGD FVGTAAHLVQ
490 500 510 520 530 540
PRGPLRWLDP GAFGTLGVGA GFALGAKLCR PDAEVWCLFG DGAFGYSLIE FDTFVRHKIP
550 560 570 580 590 600
VMALVGNDAG WTQISREQVP SLGSNVACGL AYTDYHKAAM GLGARGLLLS RENEDQVVKV
610 620 630
LHDAQQQCRD GHPVVVNILI GRTDFRDGSI AV
CATM prediction
The sequence of ILVBL_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 10 20 30 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | AGSLFASFLLLACGTLVAALLGAAHRL | 7.3 | -48.0° | 0.4 | 47.0 | -17.1 |
| Model 2 | AGSLFASFLLLACGTLVAALLGAAHRL | 6.9 | -43.1° | 0.0 | 33.7 | -1.6 |
| Prolines* | AGSLFPSFLLLACGTLVAALLGAAHRL |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 23, GLY, HA1 | A, 20, LEU, O | 3.37Å |
| B, 24, THR, HA | A, 23, GLY, O | 3.33Å |
| A, 23, GLY, HA1 | B, 20, LEU, O | 3.37Å |
| A, 24, THR, HA | B, 23, GLY, O | 3.33Å |
